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Summary of histological analysis of RPE degeneration in Rev-erbα+/+ and Rev-erbα−/− mice (incidences/eyes examined).
| Rev-erbα+/+ eyes | RPE pathology | |||
|---|---|---|---|---|
| Age (month) | Number of eyes | Hyperpigmentation | Hypopigmentation | Drusen-like deposit |
| 5–6 | 5 | 0/5 | 0/5 | 0/5 |
| 12–13 | 8 | 1/8 | 0/8 | 0/8 |
| 17–18 | 8 | 3/8 | 2/8 | 0/8 |
| Rev-erbα−/− eyes | RPE pathology | |||
| Age (month) | Number of eyes | Hyperpigmentation | Hypopigmentation | Drusen-like deposit |
| 5–6 | 10 | 3/10 | 2/10 | 0/10 |
| 12–13 | 17 | 16/17 | 8/17 | 2/17 |
| 17–18 | 9 | 9/9 | 9/9 | 1/9 |
