Table 3.
Adjusted odds ratios (OR) and 95% confidence intervals for glioma or meningioma risk and cumulative RF E-field exposure (ICNIRP ratio2-years) for various exposure lags and time windows. INTEROCC study: Data from Australia, Canada, France, Germany, Israel, New Zealand and United Kingdom, 2000–2004.
| Glioma | Meningioma | |||||
|---|---|---|---|---|---|---|
| RF E-field cumulative exposure (ICNIRP ratio2-years)b | Cases (n) | Controls (n) | ORa (95% confidence interval) | Cases (n) | Controls (n) | ORa (95% confidence interval) |
| 1-year lag | ||||||
| Non exposedc | 1,718 | 4,734 | 1.00 (ref.) | 1,744 | 4,566 | 1.00 (ref.) |
| <0.63 | 102 | 277 | 0.75 (0.59, 0.96) | 63 | 251 | 0.84 (0.62, 1.13) |
| 0.63≥6.22 | 57 | 135 | 0.82 (0.59, 1.14) | 18 | 111 | 0.69 (0.41, 1.16) |
| 6.22≥40.7 | 40 | 82 | 0.92 (0.62, 1.37) | 20 | 72 | 1.24 (0.73, 2.10) |
| ≥40.7 | 24 | 55 | 0.87 (0.53, 1.44) | 13 | 49 | 1.08 (0.57, 2.06) |
| 5-year lag | ||||||
| Non exposed | 1,718 | 4,734 | 1.00 (ref.) | 1,744 | 4,563 | 1.00 (ref.) |
| <0.46 | 82 | 246 | 0.69 (0.53, 0.90) | 54 | 223 | 0.84 (0.61, 1.15) |
| 0.46≥5.66 | 53 | 122 | 0.83 (0.59, 1.17) | 20 | 103 | 0.80 (0.48, 1.31) |
| 5.66≥40.7 | 33 | 72 | 0.89 (0.58, 1.37) | 20 | 61 | 1.51 (0.88, 2.57) |
| ≥40.7 | 20 | 49 | 0.81 (0.47, 1.39) | 11 | 44 | 1.01 (0.50, 2.03) |
| 10-year lag | ||||||
| Non exposed | 1,718 | 4,734 | 1.00 (ref.) | 1,744 | 4,563 | 1.00 (ref.) |
| <0.27 | 66 | 212 | 0.64 (0.48, 0.86) | 47 | 191 | 0.86 (0.61, 1.21) |
| 0.27≥4.93 | 38 | 104 | 0.73 (0.50, 1.08) | 18 | 91 | 0.84 (0.50, 1.43) |
| 4.93≥34.7 | 30 | 63 | 0.92 (0.58, 1.45) | 15 | 52 | 1.36 (0.74, 2.49) |
| ≥34.7 | 17 | 43 | 0.79 (0.44, 1.42) | 9 | 38 | 0.95 (0.44, 2.05) |
| 5–9 years | ||||||
| Non exposed | 1,718 | 4,721 | 1.00 (ref.) | 1,744 | 4,550 | 1.00 (ref.) |
| <0.42 | 58 | 139 | 0.84 (0.61, 1.17) | 22 | 124 | 0.60 (0.38, 0.97) |
| 0.42≥4.48 | 32 | 67 | 0.93 (0.60, 1.44) | 18 | 53 | 1.48 (0.84, 2.61) |
| 4.48≥18.9 | 18 | 40 | 0.82 (0.46, 1.47) | 8 | 38 | 1.08 (0.66, 2.39) |
| ≥18.9 | 12 | 27 | 0.90 (0.44, 1.83) | 6 | 23 | 1.03 (0.45, 2.63) |
| 1–4 years | ||||||
| Non exposed | 1,718 | 4,721 | 1.00 (ref.) | 1,744 | 4,553 | 1.00 (ref.) |
| <0.36 | 48 | 139 | 0.69 (0.49, 0.98) | 23 | 123 | 0.60 (0.38, 0.96) |
| 0.36≥3.46 | 30 | 69 | 0.85 (0.54, 1.35) | 13 | 51 | 1.13 (0.60, 2.14) |
| 3.46≥13.7 | 18 | 42 | 0.77 (0.44, 1.37) | 6 | 37 | 0.86 (0.35, 2.13) |
| ≥13.7 | 19 | 27 | 1.38 (0.75, 2.54) | 9 | 26 | 1.30 (0.58, 2.91) |
Odds ratio (OR) from conditional logistic regression models, matched by 5-year age group, sex, country, and region, and adjusted by education. Confidence intervals (CIs) based on Wald test.
Exposure categories based on irregular quantiles of the cumulative exposure distribution of controls (i.e. 50th, 75th, and 90th percentiles).
Figures for non-exposed cases and controls include only subjects who were never exposed (i.e. 1-year lag). Numbers do not coincide if strata without cases or controls were excluded.