TABLE 4.
Comparisons of targeted neuropsychiatric symptoms and apathy main factors among patients with SIVD, AD, and NC.
| SIVD |
AD |
NC |
|||
| N = 23 | N = 34 | N = 23 | P | Controlled by age and education | |
| Neuropsychiatric Inventory—total | 9.3 (8.65) | 5.9 (8.23) | 4.3 (5.31) | 0.089 | n.s. |
| Beck Anxiety Inventory | 4.8 (7.38) | 4.0 (7.03) | 7.4 (9.10) | 0.293 | n.s. |
| Beck Depression Inventory | 8.4 (11.53) | 5.9 (7.93) | 7.9 (6.74) | 0.552 | n.s. |
| Apathy Evaluation Scale—total | 45.2 (14.69) | 34.4 (13.40) | 29.2 (9.34) | <0.001ab | SIVD > AD; SIVD > NC |
| —Initiation | 0.63 (1.29) | −0.08 (0.76) | −0.51 (0.57) | <0.001ab | SIVD > AD; SIVD > NC |
| —Motivation | 0.32 (0.97) | −0.16 (0.93) | −0.07 (1.07) | 0.168 | n.s. |
| —Sociality | 0.09 (1.05) | 0.09 (1.01) | −0.22 (0.92) | 0.437 | n.s. |
SIVD, Subcortical ischemic vascular disease; AD, Alzheimer’s disease; NC, Normal Cognition; ns, non-significant. Data presented as Mean (Standard deviation) unless stated elsewhere. Comparisons were made by using the Analysis of variance (ANOVA) and Analysis of covariance (ANCOVA). P-values < 0.05 are boldly italicized. In ANOVA, P-values < 0.05 resulting from post hoc Tukey analyses were as follows:
abetween SIVD and AD,
bbetween SIVD and NC,
cbetween AD and NC. In ANCOVA, significant results from the Bonferroni method as the post hoc test were reported. No between-group difference was noted on controlling age, education, and the Mini-Mental State Examination.