Figure 3.

Characteristics of gene mutations in three immune subtypes. (a) Tumor mutation burden of three immune subtypes. ANOVA was performed. (b) Number of mutated genes in three immune subtypes. ANOVA was performed. (c) Mutation distribution and mutation types of top five mutated genes (GNAQ, GNA11, BAP1, SF3B1, and EIF1AX) in three immune subtypes. Chi-square test was performed. *p < 0.05. (A color version of this figure is available in the online journal.)

ns: no significance; TMB: tumor mutation burden.