(a) Distribution of C3, C4, and C5 subtypes in IS1, IS2, and IS3 groups.
Chi-square test was performed. (b) Distribution of
23 immune-related signatures with significant difference within IS1,
IS2, and IS3 groups. ANOVA was performed within three groups.
*p < 0.05,
**p < 0.01,
***p < 0.001,
****p < 0.0001. (A color
version of this figure is available in the online journal.)