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. 2022 Feb 2;7(6):5176–5189. doi: 10.1021/acsomega.1c06098

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© 2022 The Authors. Published by American Chemical Society

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(a) Cyclic voltammograms of the bare SPC, streptavidin-coated SPC, EDC-NHS-linked streptavidin, probe/EDC-NHS/streptavidin/bare, and miRNA393a/probe/EDC-NHS/streptavidin/bare electrodes immersed in Zobell’s solution recorded at 50 mV/s. (b) DPV analysis of streptavidin, EDC-NHS-linked streptavidin, probe/EDC-NHS/streptavidin, and miR393a/probe/EDC-NHS/streptavidin SPC electrodes at a modulation amplitude of 25 mV and modulation time of 50 ms at room temperature. (c) Repeatability cyclic voltammetry graph of four miRNA393a-probe-EDC/NHS-streptavidin biorecognition surfaces employed for 100 μM miRNA.