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. 2022 Feb 2;7(6):5176–5189. doi: 10.1021/acsomega.1c06098

Table 1. Comparison of the Analytical Performance of the Developed Biosensor Employed for microRNA Detection with Other Biosensors.

S. No amplification strategy/sensing method analyte/target molecule material used probe used linear range detection limit refs
1. fluorescence resonance energy transfer-based biosensor miRNA-167 CDs-pDNA and Fe3O4@PDA NPs DNA 0.5–100 nM 76 pM (30)
2. optical biosensor miRNA-1886 P-AuNPs C–AuNP (probe) 100–6800 fM 2 fM (31)
3. photoelectrochemical biosensor miRNA-319a indium tin oxide (ITO) electrode deposited with CuO-CuWO4 miRNA-319a-specific linear padlock DNA probe 1 fM to 0.1 nM 0.47 fM (32)
4. electrochemical biosensor miRNA-122 gold electrode capture probe: 5′-TTG TCA CAC TCC ATT TTT TTT TTT T-SH-3′ 1 pM to 100 nM 0.4 pM (33)
5. electrochemical biosensor miRNA-159a AuNPs/Au electrode DNA probe 0.01 to 10 pM 3.5 fM (34)
6. electrochemical biosensor miRNA-319a AuNPs/glassy-carbon Electrode (GCE) ssDNA probe 1000–5 pM 1.8 pM (35)
7. electrochemical biosensor microRNA-159a AuNPs/GCE ssDNA probe 0.5 pM–1.0 nM 0.17 pM (36)
8. electrochemistry miRNA ITO-coated glass slides/Ag/AgCl electrodes oligonucleotide capture probes 0.50–400 pM 0.20 pM (37)
9. streptavidin-coated SPCE miR393a streptavidin-coated SPCE DNA probe 100 nM to 100 fM 0.33 fM this work