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Summarized effects of PMN-derived EVs
| aEV | sEV | apoEV | |
|---|---|---|---|
| Maximal ROS production | ↑ | ↓ | – |
| Early ROS production | ↑ | ↓ | ↓ |
| IL-8 production of PMN | ↑ | ↓ | – |
| IL-8 secretion of HUVEC | ↑ | – | – |
| E-selectin expression of HUVEC | ↑ | – | – |
| VCAM-1 expression of HUVEC | ↑ | – | – |
| Coagulation (no TP) | – | ↑ | ↑ |
| Coagulation time (TP) | – | – | ↓ |
| Phagocytosis | – | – | – |
| Migration | – | – | – |
Arrows represent the observed statistically significant changes upon pretreatment with different EV populations compared to their adequate controls.
