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. 2022 Feb 16;21:26. doi: 10.1186/s12933-022-01450-7

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© The Author(s) 2022

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 1 — Risk of type 2 diabetes (T2D), coronary heart disease (CHD) and cerebrovascular disease (CEVD) by several sex-specific upper quantiles of ferritin levels (v. respective lowest categories). Ferritin range for highest quintile: Premenopausal women (Pre-MW) 53–950 µg/L, Postmenopausal women (Post-M) 102–1000 µg/L, Men 169–2251 µg/L. Ferritin range for highest sixtile: Pre-MW 58–950 µg/L, Post-MW 114–1000 µg/L, Men 183–2251 µg/L. Ferritin range for highest septile; Pre-MW 62–950 µg/L, Post-MW 124–1000 µg/L, Men 197–2251 µg/L. Reference (lowest quintile, sixtile or heptile). Unadjusted. Adjusted for age and sex/menopausal status. Adjusted for age, sex/menopausal status, fibrinogen levels, GGT levels, alcohol intake, smoking, systolic blood pressure, diastolic blood pressure, total cholesterol, HDL cholesterol, body mass index and year of survey. The above analysis included survey weights

Inline graphic — Risk of type 2 diabetes (T2D), coronary heart disease (CHD) and cerebrovascular disease (CEVD) by several sex-specific upper quantiles of ferritin levels (v. respective lowest categories). Ferritin range for highest quintile: Premenopausal women (Pre-MW) 53–950 µg/L, Postmenopausal women (Post-M) 102–1000 µg/L, Men 169–2251 µg/L. Ferritin range for highest sixtile: Pre-MW 58–950 µg/L, Post-MW 114–1000 µg/L, Men 183–2251 µg/L. Ferritin range for highest septile; Pre-MW 62–950 µg/L, Post-MW 124–1000 µg/L, Men 197–2251 µg/L. Reference (lowest quintile, sixtile or heptile). Unadjusted. Adjusted for age and sex/menopausal status. Adjusted for age, sex/menopausal status, fibrinogen levels, GGT levels, alcohol intake, smoking, systolic blood pressure, diastolic blood pressure, total cholesterol, HDL cholesterol, body mass index and year of survey. The above analysis included survey weights