Table 4.
Differences in CRC features and enzyme expression levels between colon and rectum
| Geographic and clinical information | ||||||
|---|---|---|---|---|---|---|
| Features | Colon | Rectum | ||||
| Cases n (%) | 61 (64.2) | 34 (35.8) | ||||
| % of Old (Young) | 62.3 (37.7) | 61.8 (38.2) | ||||
| % of Female (Male) | 49.2 (50.8) | 47.1 (52.9) | ||||
| % of AA (CA)* | 63.9 (36.1) | 47.1 (52.9) | ||||
| % of + Margin (− Margin) | 13.3 (86.7) | 28.1 (71.9) | ||||
| % High Stage (Low Stage) | 63.9 (36.1) | 60 (40) | ||||
| % of Expired (Survived) | 59 (41) | 65 (35) | ||||
| Survival time (month)** | 46 | 56.4 | ||||
| Expression levels of CE metabolism related enzymes | ||||||
| Enzymes | Colon | Rectum | ||||
| BCT | CRC | P value | BCT | CRC | P value | |
| ACAT1 (n/mean ± SD) | 53/5.3 ± 1.9 | 60/2.9 ± 2.2 | 0.0001 | 29/5.3 ± 2.2 | 25/4.6 ± 2.6 | 0.24 |
| ACAT2 (n/mean ± SD) | 49/5.4 ± 2.1 | 60/2.25 ± 1.8 | 0.71 | 26/5.5 ± 2.1 | 22/6.2 ± 1.9 | 0.54 |
| NCEH1 (n/mean ± SD) | 53/4.1 ± 1.9 | 60/4.3 ± 1.8 | 0.51 | 29/3.5 ± 2.0 | 26/4.2 ± 1.7 | 0.14 |
| LAL (n/mean ± SD) | 53/3.8 ± 1.7 | 55/6.27 ± 1.8 | 0.0001 | 2.9/3.6 ± 1.8 | 33/6.2 ± 1.3 | 0.0001 |
* The difference is significant, P < 0.05. ** The time from diagnosis to date of expiration