Table 8.
Paired differences of EQ-5D-Y-3L and EQ-5D-Y-5L Level Sum Score (LSS) at baseline, 24 h and 48 h
| Baseline LSS | 24 h LSS | Paired differences | |||
|---|---|---|---|---|---|
| Mean (SD) | Mean (SD) | Mean (SD) | p | Effect Size (95% CI) | |
| All (n = 77) | |||||
| EQ-5D-Y-5L | 13.64 (3.93) | 12.36 (3.89) | 1.27 (3.01) | < 0.001 | 0.43 (0.19, 0.66) |
| EQ-5D-Y-3L | 9.55 (2.21) | 8.77 (2.05) | 0.78 (1.93) | < 0.001 | 0.40 (0.17, 0.64) |
| No change (n = 43) | |||||
| EQ-5D-Y-5L | 13.56 (3.57) | 12.79 (3.18) | 0.67 (2.83) | 0.126 | 0.24 (− 0.07, 0.54) |
| EQ-5D-Y-3L | 9.42 (2.28) | 8.84 (1.80) | 0.58 (1.78) | 0.038 | 0.33 (0.02, 0.63) |
| Improve (n = 22) | |||||
| EQ-5D-Y-5L | 13.82 (4.54) | 11.09 (4.42) | 2.73 (2.91) | < 0.001 | 0.94 (0.42, 1.43) |
| EQ-5D-Y-3L | 10.00 (1.98) | 8.45 (2.37) | 1.55 (2.30) | 0.005 | 0.67 (0.20, 1.13) |
| Worsen (n = 12) | |||||
| EQ-5D-Y-5L | 13.58 (4.32) | 12.83 (4.59) | 0.75 (3.11) | 0.421 | 0.24 (− 0.34, 0.81) |
| EQ-5D-Y-3L | 9.17 (2.44) | 9.08 (2.39) | 0.08 (1.31) | 0.830 | 0.06 (− 0.50, 0.63) |
| 24 h LSS | 48 h LSS | ||||
|---|---|---|---|---|---|
| All (n = 71) | |||||
| EQ-5D-Y-5L | 12.38 (3.79) | 11.51 (3.76) | 0.87 (3.15) | 0.022 | 0.28 (0.04, 0.51) |
| EQ-5D-Y-3L | 8.82 (2.00) | 8.51 (1.97) | 0.31 (1.70) | 0.128 | 0.18 (− 0.05, 0.41) |
| No change (n = 42) | |||||
| EQ-5D-Y-5L | 13.62 (4.22) | 12.55 (3.83,0.59) | 1.07 (3.10) | 0.031 | 0.35 (0.03,0.66) |
| EQ-5D-Y-3L | 9.50 (2.17) | 8.90 (1.97) | 0.60 (1.98) | 0.058 | 0.30 (− 0.01,0.61) |
| Improve (n = 20) | |||||
| EQ-5D-Y-5L | 13.30 (4.18) | 12.20 (3.74) | 1.10 (2.92) | 0.108 | 0.38 (− 0.08, 0.82) |
| EQ-5D-Y-3L | 9.20 (2.44) | 8.60 (2.06) | 0.60 (1.76) | 0.144 | 0.34 (− 0.11, 0.79) |
| Worsen (n = 9) | |||||
| EQ-5D-Y-5L | 12.00 (4.12) | 13.22 (4.49) | − 1.22 (3.70) | 0.351 | − 0.33 (− 0.99,0.35) |
| EQ-5D-Y-3L | 8.89 (2.09) | 9.22 (1.92) | − 0.33 (1.12) | 0.397 | − 0.30 (− 0.96,0.38) |
| Baseline LSS | 48 h LSS | ||||
|---|---|---|---|---|---|
| All (n = 71) | |||||
| EQ-5D-Y-5L | 13.56 (4.01) | 8.51 (1.97) | 5.06 (3.45) | < 0.001 | 1.46 (1.12, 1.79) |
| EQ-5D-Y-3L | 9.58 (2.19) | 8.51 (1.97) | 1.07 (2.08) | < 0.001 | 0.52 (0.26, 0.76) |
| No change (n = 32) | |||||
| EQ-5D-Y-5L | 13.66 (3.21) | 11.84 (3.49) | 1.81 (3.41) | 0.005 | 0.53 (0.16, 0.90) |
| EQ-5D-Y-3L | 9.69 (1.75) | 8.81 (1.96) | 0.88 (2.11) | 0.025 | 0.42 (0.05, 0.77) |
| Improve (n = 29) | |||||
| EQ-5D-Y-5L | 13.69 (4.89) | 11.34 (3.88) | 2.35 (3.78) | 0.002 | 0.62 (0.22,1.01) |
| EQ-5D-Y-3L | 9.55 (2.47) | 8.17 (1.98) | 1.38 (2.13) | 0.002 | 0.65 (0.24, 1.05) |
| Worsen (n = 10) | |||||
| EQ-5D-Y-5L | 12.90 (3.81) | 10.9 (4.53) | 2.00 (3.68) | 0.120 | 0.54 (− 0.13, 1.20) |
| EQ-5D-Y-3L | 9.30 (2.75) | 8.50 (2.01) | 0.80 (1.93) | 0.223 | 0.41 (− 0.24, 1.05) |
Calculated using EQ-5D-Y-3L/ EQ-5D-5L level sum scores (LSS), a higher score indicates a worse health state, LSS, level sum score; SD, standard deviation; CI, Confidence Interval