Table 4.
Period | ||||||
---|---|---|---|---|---|---|
day 1–14 | day 15–28 | day 29–42 | day 43–56 | day > 56 | p-value for overall analysis | |
No. of episodes | 436 | 382 | 180 | 123 | 96 | |
No. of CLABSIs | 13 | 22 | 10 | 12 | 19 | |
Time at risk in days | 5866 | 4130 | 2075 | 1572 | 4979 | |
Incidence rate per 1000 catheter days (95% CI) | 2.2 (1.3–3.8) | 5.3 (3.5–8.1) | 4.8 (2.6–9.0) | 7.6 (4.3–13.4) | 3.8 (2.4–6.0) | |
IRR crude (95% CI) | 1 (ref.) | 2.4 (1.2–4.8) | 2.2 (0.95–5.0) | 3.4 (1.6–7.5) | 1.7 (0.85–3.5) | 0.026 |
IRR adjusted* (95% CI) | 1 (ref.) | 2.4 (1.2–4.8) | 1.8 (0.77–4.1) | 2.8 (1.3–6.2) | 1.6 (0.80–3.4) | 0.067 |
CI, confidence interval; IRR, incidence rate ratio
*Adjusted for aplastic anaemia and autologous stem cell transplantation