Figure 1.

Surface ACE2 is expressed by few human arterial and capillary ECs

(A) Flow cytometric analysis showing distribution of ACE2 on CD144⁺CD31⁺ and CD144⁻CD31⁺ EC subsets derived from human aorta (n = 5), lungs (n = 10), liver (n = 5), umbilical cord (n = 5), and placenta (n = 5). (B) Quantification of (A) showing %ACE2⁺ cells in total CD31⁺ ECs, respectively, derived from these adult and fetal organs. (C) Western blotting analyses showing significantly reduced ACE2 expression in CD31⁺ than CD31⁻ lung cells (n = 5). Data are presented as mean ± SD. Differences were determined by one-way ANOVA and Tukey’s HSD post hoc test. ^∗p < 0.05