Table 2. Comparison of quality of life, asthma control, IgE, eosinophils, and skin test between groups.
| Variables | Asthma with smoking exposure (n=29) | Asthma and never smokers (n=58) | P |
|---|---|---|---|
| AQLQ, means±SD | 4.39±1.27 | 4.60±1.32 | 0.475 |
| AQLQ Symptoms | 4.65±1.20 | 4.94±1.36 | 0.331 |
| AQLQ Activity Limitation | 4.36±1.45 | 4.66±1.35 | 0.347 |
| AQLQ Emotional Function | 4.59±2.18 | 4.34±1.92 | 0.589 |
| AQLQ Environmental Stimulus | 3.43±1.78 | 3.75±1.87 | 0.449 |
| Asthma control (GINA), n (%) | 0.032 | ||
| Controlled/partly controlled | 8 (27.6) | 21 (72.4) | |
| Uncontrolled | 30 (51.7) | 28 (48.3) | |
| Asthma control test, points - median (IR) | 14 (12-16) | 17 (11.8-21) | 0.036 |
| Asthma control test (<20 points; uncontrolled), n (%) | 27 (93.1) | 37 (63.8) | 0.003 |
| Serum IgE (IU/mL), median (IR) | 74 (32-349) | 154 (46-464) | 0.169 |
| IgE classification, n (%) | 0.255 | ||
| Normal (<100) | 17 (58.6) | 25 (43.1) | |
| High (>100) | 12 (41.4) | 33 (56.9) | |
| Serum eosinophils (eosinophils/μL), means±SD | 0.29 (0.20-0.59) | 0.24 (0.12-0.59) | 0.400 |
| Sputum eosinophils, n (%) | 0.241 | ||
| Unsuitable sample (saliva), n (%) | 6 (25.0) | 21 (43.8) | |
| <3% | 13 (54.2) | 17 (35.4) | |
| ≥3% | 5 (20.8) | 10 (20.8) | |
| Skin test, n (%) | 0.007 | ||
| Positive | 10 (34.5) | 39 (67.2) | |
| Negative | 19 (65.5) | 19 (32.8) |
n: number of cases; AQLQ: Asthma Quality of Life Questionnaire; GINA: Global Initiative for Asthma; IgE: immunoglobulin E; IR: interquartile range (25th-75th percentiles). Pearson's chi-square test or Fisher's exact test for categorical variables; t-test for independent samples or Mann-Whitney test for continuous variables.