Table 1. Mean escape latency of Alzheimer’s disease (AD) and wild type (WT) mice of different ages.

Day of training/Group	5 months old	7 months old	10 months old	12 months old
Day 1
AD	50.22±5.25	54.44±6.56	56.73±2.67	59.29±1.22
WT	38.34±4.09	53.56±6.54	46.03±4.61	51.34±7.10
P	0.764	0.957	0.887	0.974
Day 2
AD	38.89±4.47	38.23±9.68	58.27±1.73	55.74±1.56
WT	36.56±3.76	29.16±4.55	45.01±4.66	46.7±7.5
P	0.893	0.773	0.594	0.536
Day 3
AD	27.73±4.48	35.96±6.9	43.07±6.24	54.19±6.88
WT	16.08±2.52	17.15±3.53	18.45±3.83	24.99±3.94
P	0.047*	0.044*	0.035*	0.028*
Day 4
AD	29.85±4.32	30.43±3.68	36.55±6.33	43.55±1.19
WT	19.54±2.94	12.93±3.65	16.87±3.39	10.18±4.16
P	0.022*	0.017*	0.033*	0.014*
Day 5
AD	17.56±2.73	24.13±4.77	26.43±6.00	38.98±4.19
WT	12.85±1.67	10.24±3.04	15.10±2.08	10.92±3.39
P	0.012*	<0.001**	0.025*	<0.001**
Day 6
AD	17.92±3.83	24.84±3.34	28.54±5.84	35.83±6.98
WT	12.73±1.78	9.79±2.77	17.57±3.61	10.97±2.7
P	0.035*	0.027*	0.013*	<0.001**

Data are reported as means±SE (n=10/group). AD: APP/PS1 double transgenic mice; WT: C57BL/6J wild type mice. *P<0.05, **P<0.01, AD groups compared to WT groups at days 1 to 6 of training (t-test).