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. 2021 Oct 26;107(3):715–723. doi: 10.1210/clinem/dgab773

Table 2.

Comparison of plasma levels of primary and secondary bile acids between men and women (n = 133)

Men (n=43) Women (n=90) P P 1
Bile Acid Mean SD Mean SD
PRIMARY (CA) CA 36.5 61.7 23.5 40.8 0.131 0.255
GCA 2.8 3.3 2.0 1.9 0.136 0.230
SECONDARY (CA) DCA 21.7 18.2 16.9 19.2 0.075 0.221
GDCA 3.0 2.4 2.0 2.1 0.067 0.288
PRIMARY (CDCA) CDCA 0.7 0.9 0.5 0.7 0.039 0.119
GCDCA 7.3 5.4 5.4 3.8 0.072 0.303
SECONDARY (CDCA) GLCA 5.1 4.6 4.6 4.3 0.374 0.976
GUDCA 21.3 17.1 16.2 20.3 0.010 0.141

Data are presented as mean and SD. P values are derived from analyses of variance (ANOVA). P1 values are derived from the analyses of covariance adjusting for body fat percentage. Plasma bile acids levels were log10 transformed.

Abbreviations: CA, cholic acid; GCA, glycocholic acid; CDCA, chenodeoxycholic acid; glycochenodeoxycholic acid. DCA, deoxycholic acid; GDCA, glycodeoxycholic acid, GLCA, glycolithocholic acid; GUDCA, glycoursodeoxycholic acid.