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(A) RSS total score decreased from baseline indicating improved rickets. (B) RGI-C global score increased indicating improved rickets. (C) Sustained healing of rickets in an 8-year-old boy. (D) RGI-C lower limb deformity score increased indicating improvement throughout the study. (E) Sustained improvement in serum alkaline phosphatase (ALP) with burosumab—note that data from week 0 to week 64 were previously reported (13).
