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Dose interruption details
| Parameter, % (n) | Lenvatinib starting dose/day | |
|---|---|---|
| 24 mg (n = 75) | 18 mg (n = 77) | |
| Number of dose interruptions | ||
| 1 | 13.3 (10) | 24.7 (19) |
| 2 | 16.0 (12) | 16.9 (13) |
| 3 | 10.7 (8) | 7.8 (6) |
| ≥4 | 34.7 (26) | 24.7 (19) |
| Maximum interruption duration in days | ||
| 1 | 4.0 (3) | 2.6 (2) |
| 2-3 | 4.0 (3) | 6.5 (5) |
| 4-7 | 10.7 (8) | 15.6 (12) |
| 8-14 | 25.3 (19) | 20.8 (16) |
| 15-28 | 22.7 (17) | 14.3 (11) |
| >28 | 8.0 (6) | 14.3 (11) |
Values are based on drug exposure data.
