Table 1.
Clinical characteristics of the study population stratified by quartile
| Pro-NT Quartile 1 | Pro-NT Quartile 2 | Pro-NT Quartile 3 | Pro-NT Quartile 4 | P for trend | |
|---|---|---|---|---|---|
| No. of participants | 1158 | 1158 | 1158 | 1158 | |
| Men, n (%) | 558 (48.2%) | 497 (42.9%) | 447 (38.6%) | 467 (40.3%) | < .001 |
| Age, mean (SD), y | 58.0 ± 6.00 | 57.7 ± 5.98 | 57.6 ± 5.96 | 57.7 ± 5.97 | .309 |
| SBP, mean (SD), mm Hg | 142.8 ± 19.7 | 141.6 ± 18.6 | 142.8 ± 19.7 | 142.2 ± 18.8 | .430 |
| Antihypertensive therapy, No. (%) | 188 (16.2%) | 197 (17%) | 180 (15.5%) | 224 (19.3%) | .112 |
| Diabetes mellitus, No. (%) | 77 (6.7%) | 100 8.7%) | 100 (8.7%) | 141 (12.3%) | < .001 |
| BMI, mean (SD) | 25.8 ± 3.84 | 25.7 ± 3.75 | 25.9 ± 4.01 | 26.0 ± 4.12 | .071 |
| LDL-C mean (SD), mmol/L | 4.16 ± 1.02 | 4.16 ± 0.96 | 4.21 ± 0.98 | 4.13 ± 0.98 | .741 |
| HDL-C mean (SD), mmol/L | 1.36 ± 0.36 | 1.39 ± 0.38 | 1.39 ± 0.37 | 1.39 ± 0.38 | .018 |
| Current smokers, n (%) | 298 (25.7%) | 278 (24.0%) | 290 (25.0%) | 354 (30.6%) | .007 |
Abbreviations: BMI, body mass index; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; Pro-NT, proneurotensin; SBP, systolic blood pressure.