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. Author manuscript; available in PMC: 2022 Jul 27.
Published in final edited form as: Nat Microbiol. 2022 Jan 27;7(2):262–276. doi: 10.1038/s41564-021-01050-3

Extended Data Fig. 6. Patients with overproduction of Bacteroides vulgatus proteases have increased endoscopic and histological severity.

Extended Data Fig. 6

a, Bacteroides protease production corresponds to increased endoscopic severity. The disease activity of overproducers, underproducers, and other patients are individually plotted over boxplots. Two-tailed, t-test p-values are displayed above the boxplots. Sample sizes include n=16, 14 and 71 for overproducers, underproducers and others respectively. Boxplots are defined by the median, quartiles and 1.5x inter-quartile range. b, Bacteroides protease production corresponds to a patient population with a decreased proportion of patients in histological remission. Each UC patient sample was categorized by Bacteroides vulgatus protease production category and the percent of patients in histological remission is shown in a bargraph with the number of samples in each category displayed above each bar. Histological remission is defined here as Geboes Grade 3 = 0.