Table 1.
Characteristics of the PWID cohort achieving SVR in Scotland by time of initiating treatment for HCV.
| 2000-2009 (col %) | 2010-2014 (col %) | 2015-2016 (col %) | 2017-2018 (col %) | |
|---|---|---|---|---|
| Total PWID achieving SVR∗ | 886 | 1,587 | 1,426 | 1,787 |
| NHS board of treatment | ||||
| Greater Glasgow and Clyde | 410 (46.3) | 863 (54.4) | 854 (59.9) | 1,102 (61.7) |
| Grampian/Lothian | 331 (37.4) | 421 (26.5) | 346 (24.3) | 341 (19.1) |
| Tayside | 145 (16.4) | 303 (19.1) | 226 (15.8) | 344 (19.3) |
| Treatment setting | ||||
| Hospital | 206 (23.3) | 1,109 (69.9) | 1,059 (74.3) | 983 (55.0) |
| Community | 7 (0.8) | 227 (14.3) | 259 (18.2) | 682 (38.2) |
| Prison | 11 (1.2) | 125 (7.9) | 105 (7.4) | 122 (6.8) |
| Other/not known∗∗ | 662 (74.7) | 126 (7.9) | 3 (0.2) | 0 (0.0) |
| Sex | ||||
| Female | 235 (26.5) | 349 (22.0) | 319 (22.4) | 452 (25.3) |
| Male | 651 (73.5) | 1,238 (78.0) | 1,107 (77.6) | 1,335 (74.7) |
| Age (years) | ||||
| 50+ | 86 (9.7) | 227 (14.3) | 438 (30.7) | 467 (26.1) |
| 35-49 | 498 (56.2) | 884 (55.7) | 806 (56.5) | 1,098 (61.4) |
| <35 | 302 (34.1) | 476 (30.0) | 182 (12.8) | 222 (12.4) |
| Treatment regimen | ||||
| Interferon-based | 882 (99.5) | 1,522 (95.9) | 444 (31.1) | 28 (1.6) |
| Interferon-free | 0 (0.0) | 57 (3.6) | 982 (68.9) | 1,759 (98.4) |
| Other/not known | 4 (0.5) | 8 (0.5) | 0 (0.0) | 0 (0.0) |
| Cirrhosis at time of treatment | ||||
| No | 820 (92.6) | 1,291 (81.3) | 971 (68.1) | 1,462 (81.8) |
| Yes | 66 (7.4) | 296 (18.7) | 455 (31.9) | 325 (18.2) |
| Opioid/injection hospital admission | ||||
| >3 years pre-treatment/never pre-Treatment | 771 (87.0) | 1,285 (81.0) | 1,124 (78.8) | 1,272 (71.2) |
| During treatment/in the 3 years pre-treatment | 115 (13.0) | 302 (19.0) | 302 (21.2) | 515 (28.8) |
NHS, National Health Service; PWID, people who inject drugs; SVR, sustained virological response.
∗
Achieved SVR according to the Scottish HCV clinical database. Patients can achieve SVR more than once if they were reinfected.
∗∗
Whilst treatment setting was not recorded on the clinical database during 2000-2009, the vast majority would have been hospital.