| Nervous System Disorder(N=15616) |
Acoustic neuritis |
1(0.01) |
0(0.00) |
1(0.01) |
| Acute disseminated encephalomyelitis |
0(0.00) |
2(0.05) |
1(0.01) |
| Ageusia |
106(0.91) |
32(0.80) |
138(0.88) |
| Akathisia |
1(0.01) |
0(0.00) |
1(0.01) |
| Allodynia |
3(0.03) |
1(0.03) |
4(0.03) |
| Altered state of consciousness |
1(0.01) |
5(0.13) |
6(0.04) |
| Amnesia |
5(0.04) |
3(0.08) |
8(0.05) |
| Anaesthesia |
8(0.07) |
0(0.00) |
8(0.05) |
| Anosmia |
89(0.77) |
25(0.63) |
114(0.73) |
| Anticholinergic syndrome |
0(0.00) |
1(0.03) |
1(0.01) |
| Aphasia |
6(0.05) |
8(0.20) |
14(0.09) |
| Areflexia |
0(0.00) |
4(0.10) |
4(0.03) |
| Ataxia |
2(0.02) |
2(0.05) |
4(0.03) |
| Aura |
6(0.05) |
2(0.05) |
890.05) |
| Balance disorder |
42(0.36) |
25(0.63) |
67(0.43) |
| Band sensation |
3(0.03) |
0(0.00) |
3(0.02) |
| Basal ganglia haemorrhage |
0(0.00) |
1(0.03) |
1(0.01) |
| Basilar artery occlusion |
0(0.00) |
1(0.03) |
1(0.01) |
| Bradykinesia |
2(0.02) |
0(0.00) |
1(0.01) |
| Brain oedema |
1(0.01) |
0(0.00) |
1(0.01) |
| Brain stem infarction |
0(0.00) |
1(0.03) |
1(0.01) |
| Burning sensation |
104(0.89) |
30(0.75) |
134(0.86) |
| Burning sensation mucosal |
1(0.01) |
0(0.00) |
1(0.01) |
| Carpal tunnel syndrome |
1(0.01) |
0(0.00) |
1(0.01) |
| Central nervous system lesion |
0(0.00) |
4(0.10) |
4(0.03) |
| Cerebellar haemorrhage |
0(0.00) |
1(0.03) |
1(0.01) |
| Cerebellar infarction |
0(0.00) |
1(0.03) |
1(0.01) |
| Cerebellar stroke |
0(0.00) |
1(0.03) |
1(0.01) |
| Cerebral artery occlusion |
0(0.00) |
1(0.03) |
1(0.01) |
| Cerebral haemorrhage |
0(0.00) |
6(0.15) |
6(0.04) |
| Cerebral infarction |
0(0.00) |
4(0.10) |
4(0.03) |
| Cerebral venous sinus thrombosis |
0(0.00) |
1(0.03) |
1(0.01) |
| Cerebrovascular accident |
3(0.03) |
22(0.55) |
25(0.16) |
| Cervicobrachial syndrome |
4(0.03) |
1(0.03) |
5(0.03) |
| Cervicogenic headache |
1(0.01) |
0(0.00) |
1(0.01) |
| Cholinergic syndrome |
1(0.01) |
0(0.00) |
1(0.01) |
| Clonic convulsion |
1(0.01) |
0(0.00) |
1(0.01) |
| Clumsiness |
1(0.01) |
1(0.03) |
1(0.01) |
| Cluster headache |
12(0.10) |
6(0.15) |
18(0.12) |
| Cognitive disorder |
1(0.01) |
4(0.10) |
5(0.03) |
| Cold-stimulus headache |
1(0.01) |
0(0.00) |
1(0.01) |
| Coma |
0(0.00) |
2(0.05) |
1(0.01) |
| Complex regional pain syndrome |
1(0.01) |
2(0.05) |
3(0.02) |
| Consciousness fluctuating |
0(0.00) |
2(0.05) |
1(0.01) |
| Coordination abnormal |
6(0.05) |
5(0.13) |
11(0.07) |
| Cranial nerve disorder |
2(0.02) |
2(0.05) |
4(0.03) |
| Dementia |
1(0.01) |
2(0.05) |
3(0.02) |
| Dementia of the Alzheimer's type, with delirium |
0(0.00) |
1(0.03) |
1(0.01) |
| Demyelination |
0(0.00) |
1(0.03) |
1(0.01) |
| Depressed level of consciousness |
10(0.09) |
11(0.28) |
21(0.13) |
| Disturbance in attention |
52(0.45) |
18(0.45) |
70(0.45) |
| Dizziness |
1954(16.81) |
595(14.95) |
2549 |
| Dizziness exertional |
1(0.01) |
1(0.03) |
1(0.01) |
| Dizziness postural |
50(0.43) |
29(0.73) |
79(0.51) |
| Dreamy state |
0(0.00) |
1(0.03) |
1(0.01) |
| Drooling |
0(0.00) |
1(0.03) |
1(0.01) |
| Dysaesthesia |
10(0.09) |
1(0.03) |
11(0.07) |
| Dysarthria |
11(0.09) |
14(0.35) |
25(0.16) |
| Dysgeusia |
348(2.99) |
41(1.03) |
389(2.49) |
| Dyskinesia |
11(0.09) |
4(0.10) |
15(0.10) |
| Dysstasia |
19(0.16) |
6(0.15) |
25(0.16) |
| Dystonia |
0(0.00) |
2(0.05) |
1(0.01) |
| Encephalitis post immunisation |
0(0.00) |
1(0.03) |
1(0.01) |
| Encephalopathy |
0(0.00) |
1(0.03) |
1(0.01) |
| Epilepsy |
2(0.02) |
9(0.23) |
11(0.07) |
| Essential tremor |
1(0.01) |
0(0.00) |
1(0.01) |
| Exertional headache |
2(0.02) |
1(0.03) |
3(0.02) |
| Extrapyramidal disorder |
0(0.00) |
2(0.05) |
1(0.01) |
| Facial nerve disorder |
4(0.03) |
0(0.00) |
4(0.03) |
| Facial neuralgia |
2(0.02) |
0(0.00) |
1(0.01) |
| Facial paralysis |
799).68) |
51(1.28) |
130(0.83) |
| Facial paresis |
9(0.08) |
13(0.33) |
22(0.14) |
| Facial spasm |
5(0.04) |
2(0.05) |
7(0.04) |
| Febrile convulsion |
1(0.01) |
3(0.08) |
4(0.03) |
| Fine motor skill dysfunction |
1(0.01) |
1(0.03) |
1(0.01) |
| Formication |
7(0.06) |
2(0.05) |
9(0.06) |
| Generalised tonic-clonic seizure |
2(0.02) |
7(0.18) |
9(0.06) |
| Guillain-Barre syndrome |
1(0.01) |
3(0.08) |
4(0.03) |
| Haemorrhage intracranial |
0(0.00) |
5(0.13) |
5(0.03) |
| Head discomfort |
40(0.34) |
12(0.30) |
52(0.33) |
| Head titubation |
1(0.01) |
0(0.00) |
1(0.01) |
| Headache |
5285(45.46) |
1582(39.64) |
6867(43.97) |
| Hemianaesthesia |
3(0.03) |
0(0.00) |
3(0.02) |
| Hemidysaesthesia |
1(0.01) |
0(0.00) |
1(0.01) |
| Hemihyperaesthesia |
1(0.01) |
0(0.00) |
1(0.01) |
| Hemiparaesthesia |
3(0.03) |
2(0.05) |
6(0.04) |
| Hemiparesis |
1(0.01) |
16(0.40) |
17(0.11) |
| Horner's syndrome |
0(0.00) |
1(0.03) |
1(0.01) |
| Hyperaesthesia |
16(0.14) |
5(0.13) |
21(0.13) |
| Hypersomnia |
32(0.28) |
6(0.15) |
389(0.24) |
| Hypertonia |
2(0.02) |
0(0.00) |
1(0.01) |
| Hypoaesthesia |
572(4.92) |
144(3.61) |
716(4.59) |
| Hypogeusia |
7(0.06) |
0(0.00) |
7(0.04) |
| Hypokinesia |
3(0.03) |
3(0.08) |
6(0.04) |
| Hyporeflexia |
1(0.01) |
3(0.08) |
4(0.03) |
| Hyporesponsive to stimuli |
2(0.02) |
3(0.08) |
5(0.03) |
| Hyposmia |
7(0.06) |
2(0.05) |
9(0.06) |
| Hypotonia |
10(0.09) |
3(0.08) |
13(0.08) |
| Incoherent |
1(0.01) |
0(0.00) |
1(0.01) |
| Intracranial aneurysm |
0(0.00) |
1(0.03) |
1(0.01) |
| Ischaemic stroke |
0(0.00) |
16(0.40) |
16(0.10) |
| IVth nerve paralysis |
0(0.00) |
1(0.03) |
1(0.01) |
| Lacunar infarction |
0(0.00) |
2(0.05) |
1(0.01) |
| Lacunar stroke |
0(0.00) |
2(0.05) |
1(0.01) |
| Language disorder |
2(0.02) |
3(0.08) |
5(0.03) |
| Lethargy |
212(1.82) |
139(3.48) |
351(2.25) |
| Locked-in syndrome |
0(0.00) |
1(0.03) |
1(0.01) |
| Loss of consciousness |
46(0.40) |
40(1.00) |
86(0.55) |
| Loss of proprioception |
0(0.00) |
1(0.03) |
1(0.01) |
| Memory impairment |
14(0.12) |
7(0.18) |
21(0.13) |
| Mental impairment |
7(0.06) |
1(0.03) |
8(0.05) |
| Migraine |
255(2.19) |
121(3.03) |
376(2.41) |
| Migraine with aura |
17(0.15) |
5(0.13) |
22(0.14) |
| Migraine without aura |
1(0.01) |
0(0.00) |
1(0.01) |
| Mononeuropathy |
0(0.00) |
1(0.03) |
1(0.01) |
| Monoparesis |
2(0.02) |
3(0.08) |
5(0.03) |
| Monoplegia |
3(0.03) |
1(0.03) |
4(0.03) |
| Motor dysfunction |
2(0.02) |
0(0.00) |
1(0.01) |
| Movement disorder |
13(0.11) |
2(0.05) |
15(0.10) |
| Multiple sclerosis |
0(0.00) |
1(0.03) |
1(0.01) |
| Multiple sclerosis relapse |
1(0.01) |
1(0.03) |
1(0.01) |
| Muscle contractions involuntary |
7(0.06) |
2(0.05) |
9(0.06) |
| Muscle spasticity |
0(0.00) |
1(0.03) |
1(0.01) |
| Muscle tone disorder |
0(0.00) |
1(0.03) |
1(0.01) |
| Myasthenia gravis |
0(0.00) |
2(0.05) |
1(0.01) |
| Myelitis transverse |
0(0.00) |
1(0.03) |
1(0.01) |
| Myoclonus |
2(0.02) |
2(0.05) |
4(0.03) |
| Narcolepsy |
0(0.00) |
1(0.03) |
1(0.01) |
| Nerve compression |
3(0.03) |
0(0.00) |
3(0.02) |
| Nervous system disorder |
5(0.04) |
0(0.00) |
5(0.03) |
| Neuralgia |
37(0.32) |
12(0.30) |
49(0.31) |
| Neuralgic amyotrophy |
0(0.00) |
3(0.08) |
3(0.02) |
| Neuritis |
2(0.02) |
0(0.00) |
1(0.01) |
| Neurological symptom |
3(0.03) |
3(0.08) |
7(0.04) |
| Neuropathy peripheral |
12(0.10) |
5(0.13) |
17(0.11) |
| New daily persistent headache |
1(0.01) |
0(0.00) |
1(0.01) |
| Noninfective encephalitis |
0(0.00) |
1(0.03) |
1(0.01) |
| Nystagmus |
2(0.02) |
3(0.08) |
5(0.03) |
| Occipital neuralgia |
1(0.01) |
0(0.00) |
1(0.01) |
| Optic neuritis |
1(0.01) |
1(0.03) |
1(0.01) |
| Orthostatic intolerance |
1(0.01) |
0(0.00) |
1(0.01) |
| Paraesthesia |
901(7.75) |
201(5.04) |
1102(7.06) |
| Paralysis |
8(0.07) |
10(0.25) |
18(0.12) |
| Paraparesis |
0(0.00) |
1(0.03) |
1(0.01) |
| Paresis |
5(0.04) |
2(0.05) |
7(0.04) |
| Paresis cranial nerve |
1(0.01) |
0(0.00) |
1(0.01) |
| Parkinsonian gait |
1(0.01) |
0(0.00) |
1(0.01) |
| Parkinsonism |
0(0.00) |
1(0.03) |
1(0.01) |
| Parosmia |
24(0.21) |
4(0.10) |
28(0.18) |
| Partial seizures |
1(0.01) |
0(0.00) |
1(0.01) |
| Peripheral sensory neuropathy |
0(0.00) |
3(0.08) |
3(0.02) |
| Peroneal nerve palsy |
0(0.00) |
1(0.03) |
1(0.01) |
| Persistent postural-perceptual dizziness |
1(0.01) |
0(0.00) |
1(0.01) |
| Petit mal epilepsy |
3(0.03) |
1(0.03) |
4(0.03) |
| Polyneuropathy |
1(0.01) |
0(0.00) |
1(0.01) |
| Poor quality sleep |
22(0.19) |
4(0.10) |
26(0.17) |
| Posterior reversible encephalopathy syndrome |
0(0.00) |
1(0.03) |
1(0.01) |
| Postictal state |
2(0.02) |
0(0.00) |
1(0.01) |
| Presyncope |
177(1.52) |
79(1.98) |
256(1.64) |
| Primary headache associated with sexual activity |
1(0.01) |
0(0.00) |
1(0.01) |
| Psychogenic seizure |
1(0.01) |
1(0.03) |
1(0.01) |
| Psychomotor hyperactivity |
3(0.03) |
1(0.03) |
5(0.03) |
| Radial nerve palsy |
0(0.00) |
1(0.03) |
1(0.01) |
| Radiculitis brachial |
0(0.00) |
1(0.03) |
1(0.01) |
| Radiculopathy |
2(0.02) |
1(0.03) |
3(0.02) |
| Reduced facial expression |
0(0.00) |
1(0.03) |
1(0.01) |
| Restless legs syndrome |
7(0.06) |
3(0.08) |
10(0.06) |
| Retinal migraine |
0(0.00) |
1(0.03) |
1(0.01) |
| Reversible cerebral vasoconstriction syndrome |
0(0.00) |
1(0.03) |
1(0.01) |
| Sciatica |
7(0.06) |
2(0.05) |
9(0.06) |
| Sedation |
1(0.01) |
1(0.03) |
1(0.01) |
| Seizure |
16(0.14) |
40(1.00) |
56(0.36) |
| Seizure like phenomena |
2(0.02) |
3(0.08) |
5(0.03) |
| Sensory disturbance |
30(0.26) |
7(0.18) |
37(0.24) |
| Sensory loss |
10(0.09) |
9(0.23) |
19(0.12) |
| Serotonin syndrome |
1(0.01) |
0(0.00) |
1(0.01) |
| Sinus headache |
33(0.28) |
14(0.35) |
47(0.30) |
| Slow response to stimuli |
2(0.02) |
0(0.00) |
1(0.01) |
| Slow speech |
3(0.03) |
0(0.00) |
3(0.02) |
| Small fibre neuropathy |
0(0.00) |
1(0.03) |
1(0.01) |
| Somnolence |
167(1.44) |
49(1.23) |
216(1.38) |
| Speech disorder |
17(0.15) |
18(0.45) |
35(0.22) |
| Status epilepticus |
0(0.00) |
2(0.05) |
1(0.01) |
| Stiff leg syndrome |
0(0.00) |
1(0.03) |
1(0.01) |
| Stupor |
1(0.01) |
1(0.03) |
1(0.01) |
| Subarachnoid haemorrhage |
2(0.02) |
1(0.03) |
3(0.02) |
| Sudden onset of sleep |
1(0.01) |
0(0.00) |
1(0.01) |
| Syncope |
140(1.20) |
99(2.48) |
239(1.53) |
| Taste disorder |
50(0.43) |
11(0.28) |
61(0.39) |
| Tension headache |
45(0.39) |
18(0.45) |
63(0.40) |
| Thunderclap headache |
0(0.00) |
1(0.03) |
1(0.01) |
| Tongue biting |
1(0.01) |
0(0.00) |
1(0.01) |
| Tonic clonic movements |
2(0.02) |
0(0.00) |
1(0.01) |
| Tonic convulsion |
1(0.01) |
1(0.03) |
1(0.01) |
| Transient global amnesia |
0(0.00) |
3(0.08) |
3(0.02) |
| Transient ischaemic attack |
3(0.03) |
9(0.23) |
12(0.08) |
| Tremor |
257(2.21) |
128(3.21) |
385(2.47) |
| Trigeminal neuralgia |
5(0.04) |
1(0.03) |
6(0.04) |
| Trigeminal neuritis |
1(0.01) |
0(0.00) |
1(0.01) |
| Tunnel vision |
10(0.09) |
3(0.08) |
13(0.08) |
| Typical aura without headache |
1(0.01) |
0(0.00) |
1(0.01) |
| Unresponsive to stimuli |
10(0.09) |
37(0.93) |
47(0.30) |
| Vestibular migraine |
0(0.00) |
11(0.03) |
1(0.01) |
| Visual field defect |
3(0.03) |
3(0.08) |
6(0.04) |
| Writer's cramp |
0(0.00) |
1(0.03) |
1(0.01) |
| Investigations (N=22) |
Angiogram cerebral abnormal |
0(0.00) |
1(5.88) |
1(4.55) |
| Brain natriuretic peptide increased |
0(0.00) |
2(0.05) |
2(9.09) |
| Carotid bruit |
0(0.00) |
1(5.88) |
1(4.55) |
| Computerised tomogram head abnormal |
2(40.00) |
0(0.00) |
2(9.09) |
| CSF protein increased |
0(0.00) |
2(11.76) |
2(9.09) |
| Electroencephalogram abnormal |
0(0.00) |
1(5.88) |
1(4.55) |
| Magnetic resonance imaging brain abnormal |
1(20.00) |
6(35.29) |
7(31.82) |
| Magnetic resonance imaging spinal abnormal |
0(0.00) |
1(5.88) |
1(4.55) |
| Neurological examination abnormal |
1(20.00) |
2(11.76) |
3(13.64) |
| NIH stroke scale abnormal |
0(0.00) |
1(5.88) |
1(4.55) |
| Sensory level abnormal |
1(20.00) |
0(0.00) |
1(4.55) |
