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. Author manuscript; available in PMC: 2022 Aug 1.
Published in final edited form as: J Immunol. 2022 Jan 7;208(3):732–744. doi: 10.4049/jimmunol.2100184

Figure 6: Siglec-F promotes STAT6 phosphorylation but also enhances effector release from IL-33-stimulated eosinophils of STAT6-deficient mice.

Figure 6:

A) Western blots for indicated targets from wild-type BMDE stimulated for 4 hrs or 24 hrs with anti-Siglec-F or isotype control antibody and optionally IL-33. B) and C) ELISA results from stimulated BMDE cultures of 4get_STAT6−/− and 4get_BALB/c mice (B) or IL-4/IL-13−/− and CD45.1_BALB/c mice (C). Results show mean ± SEM of technical triplicates of one BMDE culture representative for two biologically distinct cultures per genotype. Two-way ANOVA with Bonferroni posttests; *p <0.05, ***p <0.001.