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. 2022 Feb 17;117(1):6. doi: 10.1007/s00395-022-00917-8

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© The Author(s) 2022, corrected publication 2022

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Fig. 5 — Novel risk genes were associated with lipid traits. a Data from UK Biobank (UKB) indicated that lead variants inside the boundary of risk genes were associated with lipid traits with Bonferroni-corrected significance levels (*P < 8.09e−6), or by genome-wide significance (**P < 5e−8). b Expression levels of novel genes were likewise associated with lipid traits and aortic lesion area in an atherosclerosis mouse model from the hybrid mouse diversity panel (HMDP). *P < 0.05; **FDR < 0.05. LDL-C low-density lipoproteins cholesterol, VLDL-C very low-density lipoprotein cholesterol, HDL-C high density lipoproteins cholesterol, APOA apolipoprotein A, APOB apolipoprotein B, TC total cholesterol, TG triglycerides, FFA free fatty acid