Table 1.

18 TWAS genes residing outside of published GWAS loci

Cytoband	Gene	Tissue	Z score	SE	P value	Froma
2p22.3	NLRC4	LIV	− 3.383	0.044	3.04E−06	STARNET
3q21.3	TXNRD3	VAF	2.566	0.059	1.36E−06	STARNET
4p14	FAM114A1	VAF	4.026	0.050	3.44E−09	GTEx
4p14	FAM114A1	BLD	4.845	0.037	1.80E−06	GTEx
5p13.2	EGFLAM	COR	5.596	0.047	7.70E−10	GTEx
6q16.1	UFL1	MAM	− 5.246	0.038	1.62E−06	STARNET
6q16.1	UFL1	BLD	− 4.687	0.038	8.70E−05	STARNET
6q16.1	UFL1	BLD	− 4.955	0.042	3.96E−07	GTEx
6q21	WASF1	SF	4.320	0.059	1.91E−06	STARNET
6q25.3	EZR	LIV	− 3.187	0.025	3.53E−06	STARNET
9p21.3	FOCAD	VAF	8.348	0.068	1.44E−12	GTEx
9q34.3	SDCCAG3	SKLM	− 3.015	0.061	1.74E−06	STARNET
12p11.21	TSPAN11	VAF	2.285	0.065	1.79E−07	STARNET
12p12.3	MGP	SF	− 3.412	0.040	5.67E−07	GTEx
12q14.3	CAND1	VAF	− 2.355	0.030	1.19E−07	GTEx
16p11.2	STX4	COR	3.347	0.056	2.59E−06	GTEx
16q22.1	WWP2	AOR	4.491	0.029	5.67E−06	STARNET
16q22.1	WWP2	AOR	6.570	0.031	1.19E−07	GTEx
16q24.3	GAS8	LIV	0.189	0.041	8.32E−07	GTEx
19p13.11	HOMER3	SKLM	4.647	0.030	3.52E−08	GTEx
19q13.32	KPTN	LIV	− 3.076	0.076	2.17E−06	STARNET
20q13.33	RGS19	LIV	− 4.913	0.028	1.52E−06	GTEx
20q13.33	RGS19	VAF	− 4.545	0.030	4.63E− 07	GTEx
20q13.33	RGS19	SKLM	− 5.026	0.024	1.42E−06	STARNET
20q13.33	RGS19	SKLM	− 5.298	0.018	9.29E−07	GTEx

TWAS transcriptome-wide association study, STARNET the Stockholm-Tartu Atherosclerosis Reverse Network Engineering panel, GTEx the Genotype-Tissue Expression panel, AOR aorta, COR coronary artery, MAM mammary artery, BLD blood, LIV liver, SF subcutaneous fat, VAF visceral abdominal fat, SKLM skeletal muscle

^aAssociation statistics from either STARNET- or GTEx-based models