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. 2022 Feb 14;23(3):301–318. doi: 10.1007/s40257-022-00673-4

Table 1.

von den Driesch criteria for diagnosis of Sweet syndrome. Both the major criteria and two of the four minor criteria must be met for diagnosis [29]

Major criteria Minor criteria
1. Abrupt onset of painful erythematous plaques or nodules 1. Pyrexia > 38 °C
2. Histopathologic evidence of a dense neutrophilic infiltrate without evidence of leukocytoclastic vasculitis 2. Association with an underlying hematological or visceral malignancy, inflammatory disease, or pregnancy, or preceded by an upper respiratory or gastrointestinal tract infection or vaccination
3. Excellent response to systemic corticosteroids or potassium iodide

4. Elevation of three of the four laboratory values:

(i) erythrocyte sedimentation rate > 20 mm/h

(ii) positive C-reactive protein

(iii) leukocyte count > 8000

(iv) neutrophils > 70%