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. 2022 Feb 14;23(3):301–318. doi: 10.1007/s40257-022-00673-4

Table 2.

Walker and Cohen criteria for diagnosis of drug-induced Sweet syndrome. All criteria must be met for diagnosis [33]

Criterion no. Criteria
1 Abrupt onset of painful erythematous plaques or nodules
2 Histopathologic evidence of a dense neutrophilic infiltrate without evidence of leukocytoclastic vasculitis
3 Pyrexia > 38 °C
4 Temporal relationship between drug ingestion and clinical presentation or temporally related recurrence after oral challenge
5 Temporally related resolution of lesions after drug withdrawal or treatment with systemic corticosteroids