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. 2022 Feb 3;8:799497. doi: 10.3389/fmolb.2021.799497

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Copyright © 2022 Yuan, Jiang, Tang, Wang and Duan.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Knockdown of PAFAH1B3 inhibits LIHC progression. (A) The expression PAFAH1B3 in LIHC cells lines was examined by qRT-PCR assay. (B) Establishment of PAFAH1B3 knockdown cell lines in SMC-7721 and Hu7 verified by qRT-PCR assay. (C) Knockdown of PAFAH1B3 dramatically inhibits SMC-7721 and Hu7 cells proliferation examined by growth curve assay. (D, E) Knockdown of PAFAH1B3 dramatically inhibits SMC-7721 and Hu7 cells colony formation ability. (F, G) Q9 Knockdown of PAFAH1B3 dramatically inhibits SMC-7721 and Hu7 cells migration and invasion abilities.