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. 2001 Dec;39(12):4256–4263. doi: 10.1128/JCM.39.12.4256-4263.2001

TABLE 1.

Susceptibilities of five strains of five Aspergillus spp. to AMB and ITC based on MIC-0 and MIC-2, respectively, after 24 and 48 h of incubation

Drug Time (h) Species Geometric mean (range) MIC, in mg/liter, determined by the following method:
NCCLSvis NCCLSsp XTTvis XTTsp
AMB 24 A. fumigatus 0.68 (0.125–4) 0.63 (0.5–2) 0.63 (0.25–2) 0.63 (0.5–2)
A. flavus 1.19 (0.5–4) 1.20 (0.5–2) 1.11 (0.5–2) 1.15 (0.5–2)
A. nidulans 0.74 (0.25–4) 0.72 (0.25–2) 0.68 (0.25–2) 0.66 (0.25–1)
A. terreus 1.11 (0.5–4) 0.95 (0.5–4) 1.07 (0.5–2) 1.10 (0.5–2)
A. ustus 1.11 (0.5–2) 0.88 (0.5–2) 0.92 (0.5–4) 1.12 (0.5–2)
48 A. fumigatus 1.50 (1–4) 1.26 (1–4) 1.14 (0.5–4) 1.15 (0.5–4)
A. flavus 1.64 (1–4) 1.38 (1–2) 1.57 (1–4) 1.45 (1–2)
A. nidulans 1.10 (0.25–4) 0.87 (0.25–4) 0.97 (0.25–4) 0.95 (0.25–4)
A. terreus 2.89 (2–4) 2.09 (2–4) 2.64 (2–4) 2.52 (2–4)
A. ustus 1.91 (1–4) 1.36 (1–2) 1.53 (1–4) 1.47 (1–2)
ITC 24 A. fumigatus 2.39 (0.015–>32) 1.15 (0.125–>32) 1.36 (0.125–>32) 1.38 (0.125–>32)
A. flavus 0.14 (0.063–0.25) 0.10 (0.063–0.125) 0.14 (0.0125–0.5) 0.14 (0.063–0.25)
A. nidulans 0.13 (0.031–0.5) 0.13 (0.063–0.25) 0.13 (0.062–0.5) 0.10 (0.062–0.5)
A. terreus 0.09 (0.031–0.25) 0.09 (0.063–0.125) 0.12 (0.062–0.5) 0.11 (0.063–0.125)
A. ustus 0.40 (0.062–1) 0.35 (0.063–1) 0.54 (0.062–1) 0.46 (0.063–1)
48 A. fumigatus 2.89 (0.125–>32) 2.41 (0.125–>32) 2.96 (0.125–>32) 2.10 (0.063–>32)
A. flavus 0.19 (0.125–0.5) 0.12 (0.063–0.25) 0.26 (0.125–1) 0.24 (0.125–0.5)
A. nidulans 0.16 (0.062–0.25) 0.20 (0.063–2) 0.17 (0.031–0.5) 0.15 (0.031–0.5)
A. terreus 0.15 (0.062–0.5) 0.14 (0.063–0.25) 0.29 (0.062–0.5) 0.23 (0.125–0.5)
A. ustus 1.48 (0.125–>32) 0.89 (0.5–1) 3.21 (0.125–>32) 2.72 (0.25–>32)