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. 2022 Feb 13;37(4):777–789. doi: 10.1007/s00384-022-04108-8

Table 4.

Univariate and multivariate analyses of complication occurrence

Variables Univariate analysis Multivariate binary logistic regression
No complications
1693 patients
Complication
139 patients
P value Sig. Exp(B) 95% C.I. for EXP(B)
Lower Upper
Country
  Egypt 831 (92.1%) 71 (7.9%)
  Kingdom of Saudi Arabia 808 (92.2%) 68 (7.8%) 0.93
Mean age in years 29 ± 12.4 29.61 ± 13.55 0.58
Age group
  12–39 years 1338 (92.1%) 114 (7.9%)
  40–59 years 215 (93.7%) 17 (6.3%)
  > 60 50 (86.2%) 8 (13.8%) 0.16
Sex
  Male 1022 (91.9%) 90 (8.1%)
  Female 617 (92.6%) 49 (7.4%) 0.58
Period
  Pre-COVID 1065 (94.2%) 66 (5.8%) 0.0001 0.004 1.747 1.198 2.548
  COVID 574 (88.7%) 73 (11.3%)
Mean Alverado score 7.41 ± 1.36 7.49 ± 1.27 0.51
Alvarado scoring
  Low risk ≥ 4 93 (92.1%) 8 (7.9%)
  Moderate risk 5–7 439 (93.8%) 29 (6.2%) 0.31
  High risk 8–10 1107 (91.6%) 102 (8.4%)
Time from presentation to surgery (h)
  Within 24 h (early presentation) 1493 (92.8%) 115 (7.2%) 0.001 0.013 Ref
  24–72 (borderline presentation) 78 (82.1%) 17 (17.9%) 0.024 3.139 1.161 8.494
  After > 72 h (late presentation) 68 (90.7%) 7 (9.3%) 0.006 2.307 1.272 4.186
Presentation
  Non-complicated appendicitis 1494 (92.9%) 114 (7.1%) 0.234 Ref
  Complicated appendicitis
    Peritoneal abscess 18 (90%) 2 (10%) 0.004 0.104 0.533 0.250 1.139
    Peritonitis 118 (84.9%) 21 (15.1%) 0.583 0.615 0.108 3.488
    Appendicular mass 9 (81.8%) 2 (18.2%) 0.341 2.150 0.445 10.839
Mean leucocyte count 11.95 ± 3.33 12.26 ± 2.92 0.3
Approach
  Laparoscopic 693 (91.3%) 66 (8.7%) 0.23
  Open 946 (92.8%) 73 (7.2%)
Pathology of appendix
  Catarrhal appendicitis 300 (94.6%) 17 (12.2%) 0.307 1.684 0.620 4.575
  Suppurative appendicitis 961 (92.4%) 79 (7.6%) 0.003 0.499 1.257 0.648 2.437
  Gangrenous appendicitis 266 (87.5%) 38 (12.5%) 0.509 1.164 0.742 1.828
  Normal appendix 112 (95.7%) 5 (4.3%) 0.748 Ref
Perforation
  Yes 133 (79.2%) 35 (20.8%) 0.0001 0.002 7.486 2.146 26.118
  No 1506 (93.5%) 104 (9.6%)
Base status
  Healthy 1491 (93.3%) 107 (6.7%) 0.771 Ref
  Inflamed 108 (82.4%) 23 (17.6%) 0.0001 0.515 0.634 0.161 2.500
  Necrotic 40 (81.8%) 9 (18.4%) 0.965 0.980 0.403 2.384
Mean operation time in minutes 46.75 ± 8.54 49.68 ± 10.4 0.002 0.474 0.992 0.970 1.014