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. 2022 Feb 15;269(7):3723–3734. doi: 10.1007/s00415-022-10998-z

Table 3.

Mean spatio-temporal parameters of healthy controls and people with multiple sclerosis

HC
(n = 20)
pwMS mild disability
(n = 14)
pwMS moderate disability (n = 18) Test–retest × section Test–retest × group Section × group
Test Test Retest Test Retest r2 Test–retest Section Group
Cycle duration (s) 0.87 ± 0.08 0.99 ± 0.10 0.98 ± 0.08 1.09 ± 0.13 1.03 ± 0.12 0.43  < 0.001 0.53  < 0.001 0.93 0.89 0.09
Cadence (steps/min) 140.0 ± 11.8 121.9 ± 11.1 123.2 ± 9.3 111.8 ± 12.6 117.9 ± 12.1 0.45  < 0.001 0.02  < 0.001 0.95 0.63 0.01
Stance phase (% of cycle duration) 58.0 ± 2.4 60.7 ± 2.7 60.7 ± 2.0 62.3 ± 4.6 61.1 ± 3.5 0.39 0.003 0.02  < 0.001 0.58 0.01 0.18
Swing time (% of gait cycle) 42.0 ± 2.4 39.3 ± 2.7 39.3 ± 2.0 37.7 ± 4.6 38.9 ± 3.5 0.39 0.003 0.02  < 0.001 0.58 0.01 0.18
Load ratio (% of stance) 13.1 ± 2.8 10.7 ± 2.4 10.9 ± 2.4 9.0 ± 2.2 9.7 ± 2.3 0.32 0.55  < 0.001  < 0.001 1.0 0.08  < 0.001
Foot flat ratio (% of stance) 41.9 ± 7.5 51.9 ± 6.8 51.9 ± 5.6 59.5 ± 6.9 57.0 ± 5.3 0.53  < 0.001  < 0.001  < 0.001 0.98 0.12 0.03
Push ratio (% of stance) 44.9 ± 6.5 37.4 ± 6.2 37.2 ± 4.8 31.5 ± 6.0 33.4 ± 4.6 0.45  < 0.001 0.60  < 0.001 0.97 0.34 0.80
Double contact time (% of cycle duration) 15.9 ± 4.0 21.1 ± 4.2 21.2 ± 3.7 26.0 ± 11.8 22.9 ± 3.1 0.39 0.001 0.005  < 0.001 0.63 0.008 0.19
Stride length (m) 1.68 ± 0.20 1.53 ± 0.17 1.56 ± 0.13 1.33 ± 0.27 1.40 ± 0.24 0.49  < 0.001  < 0.001  < 0.001 0.85 0.006 0.35
Gait speed (m/s) 1.97 ± 0.29 1.58 ± 0.25 1.62 ± 0.21 1.27 ± 0.33 1.39 ± 0.28 0.52  < 0.001  < 0.001  < 0.001 0.94 0.07 0.03
Max angular velocity (deg/s) 538 ± 52 454 ± 53 463 ± 51 396 ± 82 426 ± 73 0.44  < 0.001 0.38  < 0.001 0.83 0.003 0.50
Foot pitch angle at heal strike (deg) 28.4 ± 5.3 24.6 ± 5.3 26.1 ± 5.4 21.9 ± 6.4 22.9 ± 7.6 0.21 0.07  < 0.001  < 0.001 0.97 0.95 0.43
Foot pitch angle at toe off (deg) − 84.6 ± 5.9 − 79.3 ± 6.2 − 78.2 ± 5.5 − 67.4 ± 13.9 − 70.8 ± 11.2 0.52  < 0.001  < 0.001  < 0.001 0.78  < 0.001 0.72
Swing width (% of stride length) 0.03 ± 0.02 0.05 ± 0.03 0.05 ± 0.01 0.06 ± 0.03 0.06 ± 0.02 0.02 0.68 0.71 0.77 0.68  < 0.001 0.09
Path length (% of stride length) 105.3 ± 3.4 105.7 ± 6.7 105.0 ± 1.3 109.2 ± 22.1 106.8 ± 3.6 0.19  < 0.001 0.11 0.005 0.23 0.003 0.85

HC Healthy control, PwMS People with MS

Mean values ± standard deviations are given for the different spatio-temporal parameters of the healthy controls and two pwMS disability groups at test and retest

Statistical analysis of the different parameters, providing the Marginal r2 effect size and the p values for the fixed effect and the cross correlations (x) between conditions (last six columns)