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. 2022 Feb 15;269(7):3723–3734. doi: 10.1007/s00415-022-10998-z

Table 4.

Variability of the spatio-temporal parameters of healthy controls and people with multiple sclerosis

HC
(n = 20)
PwMS mild disability (n = 14) PwMS moderate disability (n = 18) Test–retest × section Test–retest × group Section × group
Test Test Retest Test Retest r2 Test–retest Section Group
Cycle duration (%) 30.2 ± 0.1 0.3 ± 0.1 0.1 ± 0.1 0.8 ± 0.2 0.3 ± 0.1 0.16 0.16 0.012 0.33 0.50 0.87 0.16
Cadence (%) 0.2 ± 0.1 0.3 ± 0.1 0.1 ± 0.1 0.8 ± 0.1 0.2 ± 0.2 0.07 0.41 0.087 0.69 0.93 0.38 0.10
Stance phase (%) 1.7 ± 1.4 2.0 ± 2.0 1.5 ± 1.5 6.4 ± 3.4 4.3 ± 3.0 0.14 0.028 0.54 0.015 0.33  < 0.001 0.006
Swing time (%) 2.4 ± 2.0 3.5 ± 3.7 2.3 ± 2.4 20.3 ± 6.3 7.2 ± 5.5 0.15 0.075 0.64 0.006 0.27  < 0.001 0.008
Load ratio (%) 9.8 ± 7.1 17.7 ± 20.2 21.2 ± 24.7 21.7 ± 21.3 22.9 ± 24.6 0.07  < 0.001 0.75 0.33 0.54  < 0.001 0.36
Foot flat ratio (%) 7.4 ± 5.0 8.5 ± 8.3 10.3 ± 9.5 6.0 ± 4.3 9.3 ± 7.5 0.09  < 0.001 0.541 0.65 0.94 0.018 0.11
Push ratio (%) 6.1 ± 5.4 10.7 ± 8.7 10.2 ± 8.4 16.5 ± 6.4 17.7 ± 5.3 0.10  < 0.001 0.33 0.11 0.94 0.002 0.07
Stride length (%) 3.0 ± 1.5 2.9 ± 1.3 3.0 ± 1.5 21.2 ± 2.1 2.0 ± 2.6 0.05  < 0.001 0.14 0.43 0.69  < 0.001 0.64
Gait speed (%) 3.0 ± 1.5 2.2 ± 3.2 2.7 ± 3.0 6.8 ± 2.1 2.0 ± 2.1 0.05  < 0.001 0.5 0.22 0.38 0.008 0.95
Max angular velocity (%) 3.9 ± 3.0 5.9 ± 7.1 3.8 ± 2.8 15.9 ± 14.3 18.9 ± 18.4 0.19  < 0.001 0.83  < 0.001 0.97 0.006 0.85
Foot pitch angle at heal strike (%) 7.9 ± 4.8 20.3 ± 27.1 16.9 ± 23.0 51.7 ± 19.8 28.6 ± 26.3 0.07 0.25 0.43 0.42 0.44 0.014 0.71
Foot pitch angle at toe off (%) 3.9 ± 2.5 5.5 ± 4.7 4.8 ± 3.3 13.3 ± 13.3 21.9 ± 19.4 0.17 0.99 0.97 0.002 0.29 0.12 0.61
Swing width (%) 160.8 ± 345.4 51.9 ± 106.5 94.6 ± 28.1 38.6 ± 194.4 81.1 ± 144.2 0.10 0.88 0.025 0.005 1.00 0.88 0.004
Path length (%) 0.5 ± 0.4 2.0 ± 1.8 1.1 ± 1.6 6.4 ± 1.3 1.7 ± 1.9 0.09 0.003 0.62 0.057 0.28 0.43 0.85

HC Healthy control, PwMS People with Multiple Sclerosis

Variability ± Standard Deviations between the left and right leg of the different spatio-temporal parameters for the healthy controls and the two pwMS disability groups at Test–Retest. Statistical analysis of the different parameters, providing the Marginal r2 effect size and the p values for the fixed effect and the cross correlations (x) between conditions (last 6 columns).