Fig 1. Enterobacter cloacae ATCC 13047 is highly meropenem tolerant.

(A) Representative experiment demonstrating changes in OD₆₀₀ measurements following meropenem treatment in E. cloacae relative to E. coli. Error bars represent the average of 3 technical replicates +/- standard deviation. (B) Survival was calculated as CFU/mL from the experiment depicted in (A). The red line denotes the limit of detection. Phase images from the same experiment show cells before and after meropenem exposure to illustrate spheroplast formation in E. cloacae and lysis in E. coli (only cell debris is visible in phase image). Scale bars, 2 μm.