Table 1. Biometrics and EDP data of all samples with unequivocal results.
| Sample group | All bacteremic infection (BC positive) | All non-bacteremic bacterial infection (BC negative, excluding TB) | Proven TB | All bacterial infection negative |
|---|---|---|---|---|
| Number of samples | 23 | 28 | 4 | 13 |
| Male: Female | 0.29:1 | 0.5:1 | 1:1 | 0.7:1 |
| Median Age [IQR] (years) | 32 (25.5–51.5) | 29 (8–54) | 36 (29–43) | 17 (0.5–26.3) |
| HIV positive samples | 8/14 (57.1) | 9/16 (56.3) | 4/4 (100) | 2/7 (28.6) |
| (pos/all tested)% | ||||
| nCD64:lCD64 | ||||
| Median | 13.0 | 5.26 | 20.15 | 1.6 |
| IQR | 9.3–37. | 2.6–10.3 | 13.38–98.75 | 1.00–4.2 |
| p-value* | 0.0003 | 0.0059 | 0.005 | Not applicable |
| mCD64:lCD64 | ||||
| Median | 41.2 | 49.6 | 66.81 | 36.7 |
| IQR | 22.6–78.7 | 27.8–63.3 | 30.05–131.2 | 29.2–47.8 |
| p-value* | 0.46 | 0.28 | 0.16 | Not applicable |
| nCD64:mHLA-DR | ||||
| Median | 1.12 | 0.52 | 3.9 | 0.17 |
| IQR | 0.70–3.10 | 0.18–1.02 | 1.76–5.75 | 0.03–0.30 |
| p-value* | < 0.0001 | 0.005 | 0.004 | Not applicable |
| NE-WY | ||||
| Median | 840.0 | 765 | 827.5 | 731.0 |
| IQR | 769.0–1002.0 | 662–900 | 733.3–865.5 | 655.5–819.5 |
| p-value* | 0.0057 | 0.32 | 0.16 | Not applicable |
| NE-SFL | ||||
| Median | 57.0 | 50.4 | 54.2 | 46.2 |
| IQR | 54.6–63.9 | 46.7–53.2 | 48.7–60.6 | 42.3–48.4 |
| p-value* | 0.0007 | 0.019 | 0.036 | Not applicable |
| MO-Y | ||||
| Median | 109.9 | 103.7 | 124.5 | 107.0 |
| IQR | 95.0–114 | 98.2–109.8 | 117.4–125.8 | 93.6–109.2 |
| p-value* | 0.45 | 0.89 | 0.011 | Not applicable |
| Automated IG count | ||||
| Median | 1.900 | 1.6 | 3.0 | 0.50 |
| IQR | 0.7–3.0 | 0.8–4.2 | 1.88–4.95 | 0.40–1.1 |
| p-value* | 0.006 | 0.04 | 0.012 | Not applicable |
| Abs auto IG (x10 9 /L) | ||||
| Median | 0.1400 | 0.19 | 0.26 | 0.05 |
| IQR | 0.10–0.44 | 0.08–0.64 | 0.15–0.56 | 0.03–0.11 |
| p-value* | 0.018 | 0.001 | 0.030 | Not applicable |
*The p-values are derived from comparison with the infection negative cases.
nCD64:lCD64, neutrophil CD64:lymphocyte CD64; mCD64:lCD64, monocyte CD64:lymphocyte CD64
nCD64:mHLA-DR, neutrophil CD64:monocyte HLA-DR; NE-WY, fluorescent light distribution width of the neutrophil area; NE-SFL, fluorescent light intensity of the neutrophil area; IG%, immature granulocyte percentage; CRP, C-reactive protein; Pct, procalcitonin; Abs auto IG, absolute automated IG count.