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. 2022 Feb 17;17(2):e0263285. doi: 10.1371/journal.pone.0263285

Fig 3. Dapagliflozin mitigates pro-inflammatory response in diabetic heart rats.

Fig 3

mRNA expression of (A) interleukin-1β (Il1b), (B) interleukin-6 (Il6), (C) tumor necrosis factor (Tnf), and (D) monocyte chemoattractant protein 1 (Ccl2) of control, diabetic and dapagliflozin treated diabetic rats (D+DAPA). mRNA expressions were normalized to Rn18S mRNA expression. Bars indicate means±SDs and data were analyzed by one-way ANOVA with Holm-Sidak multiple comparisons test (n = 6/group) *p<0.05 vs. Control, **p<0.01 vs. Control, ***p<0.001 vs. Control, §p<0.05 vs. Diabetic, §§p<0.01 vs. Diabetic.