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. 2022 Feb 17;17(2):e0263285. doi: 10.1371/journal.pone.0263285

Table 3. Mean arterial pressure, heart rate and heart to body weight ratio.

Control Diabetic (D) D+DAPA
Mean arterial pressure (mmHg) 88.5±3.66 85.9±4.99 77.1±5.69
Heart rate (bpm) 444±12.9 320±25.2*** 352±28.3§
Heart to body weight ratio (%) 0.29±0.01 0.36±0.02*** 0.33±0.02§§

C, Control; D, diabetic; D+DAPA, dapagliflozin-treated diabetic.

Values indicate means±SDs and data were analyzed by one-way ANOVA with Holm-Sidak multiple comparisons test (n = 6/group).

***p<0.001 vs. Control

§p<0.05 vs. Diabetic

§§p<0.01 vs. Diabetic.