Table 3. Subgroup analyses comparing incidence rate ratios for MACE after dengue infection.
| Variables | Day 1–7 | Day 8–14 | ||||||
|---|---|---|---|---|---|---|---|---|
| N | IRR (95% CI)† | p value | N | IRR (95% CI)† | p value | |||
| Age | ||||||||
| 0–39 years | 60 | 16.66 | (6.48–42.84) | < .0001 | 60 | 3.00 | (0.40–21.54) | 0.286 |
| 40–59 years | 474 | 6.61 | (4.29–10.16) | < .0001 | 474 | 2.60 | (1.34–5.05) | 0.005 |
| ≥60 years | 1,954 | 21.12 | (18.45–24.18) | < .0001 | 1,954 | 2.34 | (1.66–3.30) | < .0001 |
| Sex | ||||||||
| Male | 1,488 | 15.94 | (13.48–18.86) | < .0001 | 1,488 | 2.16 | (1.44–3.23) | 0.000 |
| Female | 1,006 | 21.17 | (17.44–25.71) | < .0001 | 1,006 | 2.79 | (1.77–4.40) | < .0001 |
| Severity | ||||||||
| Admission case | 1,712 | 24.39 | (21.30–27.92) | < .0001 | 1,712 | 2.42 | (1.69–3.45) | < .0001 |
| Non admission case | 782 | 4.17 | (2.70–6.45) | < .0001 | 782 | 2.34 | (1.32–4.15) | 0.004 |
| With disease hospitalization | ||||||||
| Hemorrhage stroke | 234 | 10.90 | (6.80–17.49) | < .0001 | 234 | 4.33 | (2.13–8.78) | < .0001 |
| Ischemic stroke | 952 | 15.56 | (12.44–19.47) | < .0001 | 952 | 3.17 | (2.03–4.94) | < .0001 |
| Acute myocardial infarction | 544 | 13.53 | (10.13–18.06) | < .0001 | 544 | 1.16 | (0.48–2.81) | 0.737 |
| Heart failure | 810 | 27.24 | (22.67–32.73) | < .0001 | 810 | 2.45 | (1.49–4.03) | <0.001 |
MACE, major adverse cardiac event; IRR, incidence rate ratios; CI, confidence interval
† Estimated by Poisson regression with adjusted baseline characteristics