Table 2.
Treatment | Evidence-based recommendation |
---|---|
Hysteroscopic myomectomy | Decreases and removes intracavitary fibroids and improves symptoms; typically preserves the integrity of the myometrium; recommended for FIGO 0, FIGO 1, and some FIGO 2 submucosal fibroids and for patients desiring to retain fertility; associated with a 15–50% risk of recurrence [31, 41, 46] |
Abdominal myomectomy (laparoscopic, robotic, or laparotomic) | Reduces uterine volume and improves symptoms; recommended for intramural, subserosal, and very large submucosal fibroids that are not amenable to hysteroscopic resection [31] |
Endometrial ablation/myolysis | Reduces HMB; uses electrical energy, cryotherapy, heated saline, or radiofrequency energy to destroy the endometrium; recommended for premenopausal patients who do not desire future fertility [31, 41, 46] |
Radiofrequency volumetric thermal ablation | Minimally invasive; reduces fibroid volume and improves symptoms; impact on fertility requires further investigation [31] |
Hysterectomy | Advised for patients who desire definitive treatment for symptomatic fibroids; should be performed minimally invasively when possible [31, 41, 46] |
FIGO, International Federation of Gynecology and Obstetrics; HMB, heavy menstrual bleeding