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. 2022 Feb 7;16(2):e0010192. doi: 10.1371/journal.pntd.0010192

Table 2. Sensitivity and specificity of Shigella RLDT compared to qPCR.

Shigella qPCR (as the gold standard) vs RLDT
Total samples screened Samples positive by RLDT (%) Samples positive by qPCR (%) False positive False negative Sensitivity (%) Specificity (%)
Overall (includes both study 1 and study 2)
367 9 (2.5%) 9 (2.5%) 0 0 100 100
    Study 1 (Hospital-based surveillance in Bangladesh)
261 6 (2.3) 6 (2.3) 0 0 100 100
    Study 2 (overall travelers to Guatemala and Mexico)
106 3 (2.8) 3 (2.8) 0 0 100 100
    Study 2 (travelers with MSD only)
39 2 (5.1) 2 (5.1) 0 0 100 100
    Study 2 (asymptomatic travelers only)
67 1 (1.5) 1 (1.5) 0 0 100 100