Table 2. Sensitivity and specificity of Shigella RLDT compared to qPCR.
Shigella qPCR (as the gold standard) vs RLDT | ||||||
---|---|---|---|---|---|---|
Total samples screened | Samples positive by RLDT (%) | Samples positive by qPCR (%) | False positive | False negative | Sensitivity (%) | Specificity (%) |
Overall (includes both study 1 and study 2) | ||||||
367 | 9 (2.5%) | 9 (2.5%) | 0 | 0 | 100 | 100 |
Study 1 (Hospital-based surveillance in Bangladesh) | ||||||
261 | 6 (2.3) | 6 (2.3) | 0 | 0 | 100 | 100 |
Study 2 (overall travelers to Guatemala and Mexico) | ||||||
106 | 3 (2.8) | 3 (2.8) | 0 | 0 | 100 | 100 |
Study 2 (travelers with MSD only) | ||||||
39 | 2 (5.1) | 2 (5.1) | 0 | 0 | 100 | 100 |
Study 2 (asymptomatic travelers only) | ||||||
67 | 1 (1.5) | 1 (1.5) | 0 | 0 | 100 | 100 |