Table 1. Thorough description of reported cases of meningitis and meningoencephalitis due to SARS-CoV-2.
Authors | Title | Neurological Syndrome | Month/Year 1 | Country | Age | Sex | CSF RT-PCR for SARS-CoV-2 | Nasopharyngeal Swab for SARS-CoV-2 | Outcome |
---|---|---|---|---|---|---|---|---|---|
Moriguchi et al. 5 | A first case of meningitis/encephalitis associated with SARS-CoV-2 | Meningitis | April/2020 | Japan | 24 y | M | Positive | Negative | N/A |
Packwood et al . 13 | Unusual Case Report of COVID-19 presenting with Meningitis symptoms and shingles | Meningitis | August/2020 | United States | 58 y | M | N/A | Positive | Discharge |
Dharsandiya et al . 14 | SARS-CoV-2 viral sepsis with meningoencephalitis | Meningoencephalitis | June/2020 | India | 68 y | M | NP | Positive | Death |
Bernard-Valn et al . 15 | Two patients with acute meningoencephalitis concomitant with SARS-CoV-2 infection | Meningoencephalitis | September/2020 | Switzerland | 64/67 y | F | Negative | Positive | Discharge * |
Ferreira et al . 16 | Acute meningoencephalitis as initial presentation of SARS-CoV-2 Infection in pediatrics | Meningoencephalitis | November/2020 | Colombia | 5 m | N/A | Negative | Positive 2 | Discharge |
Dugue et al . 17 | Neurologic manifestations in an infant with COVID-19 | Meningoencephalitis | June/2020 | United States | 1 m | M | Negative | Positive | Discharge |
Regev et al. 18 | Pediatric Inflammatory Multisystem Syndrome with Central Nervous System involvement and hypocomplementemia following SARS-CoV-2 infection | Meningoencephalitis | August/2020 | Israel | 16 y | M | Negative | Positive | Discharge |
Al-Olama et al. 19 | COVID-19-associated meningoencephalitis complicated with intracranial hemorrhage: a case report | Meningoencephalitis | May/2020 | United Arab Emirates | 36 y | M | Positive 2 | Positive 2 | N/A |
Chaumont et al. 20 | Acute meningoencephalitis in a patient with COVID-19 | Meningoencephalitis | June/2020 | France | 69 y | M | Negative | Positive 3 | Discharge |
Publication date;
Second swab was positive;
Performed as bronchoalveolar lavage; M = Male; F = Female; N/A = Not Available; NP=Not performed;
both patients were female, had negative CSF RT-PCR for SARS-CoV-2 , and discharged; m = months; y = years.