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. Author manuscript; available in PMC: 2022 Dec 20.
Published in final edited form as: Chem Res Toxicol. 2021 Nov 24;34(12):2579–2591. doi: 10.1021/acs.chemrestox.1c00347

Scheme 1.

Scheme 1.

General synthetic route for generation of mono-alkyl-ethers of arachidonic acid methyl ester (1-4, regioisomeric mixturesa). aDepicted by the representative terminal regioisomer.