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. 2021 Jul 18;71(3):579–588. doi: 10.1007/s00262-021-03018-y

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© The Author(s) 2021

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Fig. 2 — Circulating regulatory T (Treg) cells in pseudoprogression and hyperprogression. a Gating strategies of CD4⁺CD25⁺CD127^loFoxP3⁺ Treg cells by flow cytometry. b In patients who experienced pseudoprogression, the frequency of CD4⁺CD25⁺CD127^loFoxP3⁺ Treg cells decreased significantly 7 days after initiation of treatment compared with baseline (P = 0.038). c In patients who experienced hyperprogression, the frequency of CD4⁺CD25⁺CD127^loFoxP3⁺ Treg cells increased significantly 7 days after initiation of treatment compared with baseline (P = 0.024)