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. 2022 Feb 4;12:735736. doi: 10.3389/fendo.2021.735736

Table 2.

Univariate analysis of IR, IGT, and DM.

Variables IR IGT DM
OR (95% CI) p-Value OR (95% CI) p-Value OR (95% CI) p-Value
Age 1.01 (1~1.01) <0.001 1.06 (1.05~1.06) <0.001 1.06 (1.06~1.06) <0.001
Gender
 Male 1 1 1
 Female 0.99 (0.9~1.1) 0.89 0.79 (0.7~0.89) <0.001 0.85 (0.75~0.96) 0.011
Education
 No higher education 1 1 1
 Higher education 0.8 (0.72~0.89) <0.001 0.65 (0.58~0.74) <0.001 0.62 (0.55~0.7) <0.001
Income
 No more than $100,000 1 1 1
 More than $100,000 0.75 (0.68~0.84) <0.001 0.74 (0.66~0.84) <0.001 0.72 (0.63~0.82) <0.001
Alcohol use
 No 1 1 1
 Yes 1.25 (1.12~1.4) <0.001 1.15 (1.02~1.31) 0.028 1.22 (1.07~1.39) 0.003
Smoking
 No 1 1 1
 Yes 0.93 (0.83~1.04) 0.195 0.74 (0.65~0.84) <0.001 0.76 (0.67~0.87) <0.001
Hyperuricemia
 No 1 1 1
 Yes 2.6 (2.27~2.98) <0.001 2.43 (2.11~2.79) <0.001 2.32 (2.01~2.67) <0.001
Hypertension
 No 1 1 1
 Yes 1.71 (1.53~1.91) <0.001 6.56 (5.43~7.91) <0.001 7.58 (6.1~9.42) <0.001
Hypercholesterolemia
 No 1 1 1
 Yes 1.73 (1.56~1.92) <0.001 4.14 (3.65~4.7) <0.001 4.48 (3.91~5.13) <0.001
BMI 1.18 (1.17~1.2) <0.001 1.1 (1.09~1.11) <0.001 1.09 (1.08~1.1) <0.001
Waist 1.07 (1.06~1.07) <0.001 1.05 (1.05~1.06) <0.001 1.05 (1.05~1.05) <0.001
TC 1.04 (0.99~1.09) 0.097 1.13 (1.07~1.19) <0.001 1.11 (1.05~1.17) <0.001
TG 2.06 (1.91~2.21) <0.001 1.48 (1.39~1.57) <0.001 1.44 (1.36~1.53) <0.001
HDL 0.15 (0.13~0.18) <0.001 0.41 (0.35~0.49) <0.001 0.41 (0.34~0.49) <0.001
TG/HDL 2.09 (1.94~2.25) <0.001 1.3 (1.24~1.36) <0.001 1.28 (1.22~1.34) <0.001
ALT 1.02 (1.02~1.02) <0.001 1.01 (1.01~1.01) <0.001 1.01 (1.01~1.01) <0.001
AST 1 (1~1.01) 0.174 1 (1~1.01) 0.005 1 (1~1.01) 0.032
GGT 1.01 (1.01~1.01) <0.001 1.01 (1.01~1.01) <0.001 1.01 (1.01~1.01) <0.001
ALP 1 (1~1) <0.001 1 (1~1) <0.001 1 (1~1) <0.001
BUN 1.03 (1.01~1.06) 0.009 1.32 (1.27~1.36) <0.001 1.32 (1.27~1.36) <0.001
UA 1.01 (1~1.01) <0.001 1.01 (1~1.01) <0.001 1.01 (1~1.01) <0.001

IR, insulin resistance; BMI, body mass index; ALT, alanine aminotransferase; AST, aspartate aminotransferase; ALP, alkaline phosphatase; BUN, blood urea nitrogen; GGT, γ-glutamyl transpeptidase; UA, uric acid; TC, total cholesterol; TG, triglycerides; HDL, high-density lipoprotein.