Table 3.
Outcomes | Model 1 | Model 2 | Model 3 | Model 4 | p for interaction | ||||
---|---|---|---|---|---|---|---|---|---|
OR (95% CI) | p-Value | OR (95% CI) | p-Value | OR (95% CI) | p-Value | OR (95% CI) | p-Value | ||
IR group | <0.001 | ||||||||
N1 (<30) | 2.33 (1.83~2.96) | <0.001 | 2.63 (2.02~3.43) | <0.001 | 2.02 (1.55~2.64) | <0.001 | 2.11 (1.57~2.83) | <0.001 | |
N2 (30–50) | 2.01 (1.73~2.34) | <0.001 | 2.23 (1.89~2.63) | <0.001 | 1.52 (1.31~1.78) | <0.001 | 1.52 (1.29~1.78) | <0.001 | |
N3 (50–80) | 1.87 (1.68~2.07) | <0.001 | 1.88 (1.69~2.09) | <0.001 | 1.31 (1.18~1.44) | <0.001 | 1.28 (1.16~1.41) | <0.001 | |
N4 (>80) | 3.27 (2.69~3.98) | <0.001 | 3.22 (2.63~3.94) | <0.001 | 2.23 (1.81~2.74) | <0.001 | 2.16 (1.75~2.67) | <0.001 | |
IGT group | <0.001 | ||||||||
N1 (<30) | 1.54 (1.33~1.8) | <0.001 | 1.63 (1.36~1.94) | <0.001 | 1.46 (1.21~1.75) | <0.001 | 1.41 (1.17~1.70) | <0.001 | |
N2 (30–50) | 1.31 (1.19~1.43) | <0.001 | 1.29 (1.17~1.43) | <0.001 | 1.18 (1.08~1.3) | <0.001 | 1.18 (1.07~1.29) | 0.001 | |
N3 (50–80) | 1.18 (1.11~1.26) | <0.001 | 1.19 (1.1~1.27) | <0.001 | 1.08 (1.01~1.15) | 0.016 | 1.09 (1.02~1.16) | 0.007 | |
N4 (>80) | 1.6 (1.39~1.84) | <0.001 | 1.59 (1.37~1.85) | <0.001 | 1.28 (1.1~1.48) | 0.001 | 1.22 (1.05~1.42) | 0.009 | |
DM group | <0.001 | ||||||||
N1 (<30) | 1.43 (1.24~1.65) | <0.001 | 1.51 (1.27~1.78) | <0.001 | 1.37 (1.15~1.62) | <0.001 | 1.31 (1.1~1.55) | 0.002 | |
N2 (30–50) | 1.29 (1.18~1.41) | <0.001 | 1.31 (1.19~1.44) | <0.001 | 1.2 (1.09~1.32) | <0.001 | 1.19 (1.08~1.31) | <0.001 | |
N3 (50–80) | 1.18 (1.1~1.26) | <0.001 | 1.22 (1.13~1.32) | <0.001 | 1.11 (1.04~1.2) | 0.002 | 1.13 (1.06~1.20) | <0.001 | |
N4 (>80) | 1.51 (1.32~1.73) | <0.001 | 1.53 (1.31~1.78) | <0.001 | 1.27 (1.09~1.47) | 0.002 | 1.22 (1.05~1.42) | 0.01 |
Model 1: non-adjusted. Model 2: adjusted for gender, age, and race. Model 3: Model 2 + adjusted for ALT, AST, TG, TC, GGT, ALB, and HDL. Model 4: Model 3 + adjusted for smoking, alcohol use, income, and education.
VD3, vitamin D3; IR, insulin resistance; IGT, impaired glucose tolerance; DM, diabetes mellitus; ALT, alanine aminotransferase; AST, aspartate aminotransferase; TG, triglycerides; TC, total cholesterol; GGT, γ-glutamyl transpeptidase; ALB, albumin; HDL, high-density lipoprotein.