Table 3.
Association between high plasma concentration of Apo CIII (≥10.3 mg/dL), and ischemic stroke/TIA events by different Cox Regression models (subjects with low plasma concentration of Apo CIII, <10.3 mg/dL, are considered as reference group).
| Coefficient B | SE | Hazard ratio | |
|---|---|---|---|
| Unadjusted | 1.12 | 0.47 | 3.08 (1.22–7.77) |
| Model 1 | 1.09 | 0.49 | 2.97 (1.14–7.74) |
| Model 2 | 1.05 | 0.49 | 2.86 (1.10–7.53) |
| Model 3 | 0.99 | 0.49 | 2.70 (1.03–7.13) |
| Model 4 | 1.32 | 0.57 | 3.76 (1.24–11.42) |
| Model 5 | 1.32 | 0.58 | 3.73 (1.20–11.61) |
Model 1: sex- and age-adjusted.
Model 2: adjusted for sex, age, CAD diagnosis, and atrial fibrillation.
Model 3: adjusted for sex, age, CAD diagnosis, atrial fibrillation, diabetes, and hypertension.
Model 4: adjusted for sex, age, CAD diagnosis, atrial fibrillation, diabetes, hypertension, and all plasma lipid parameters (i.e., total, LDL, and HDL-cholesterol, triglycerides, Apo AI, Apo B, and Apo E).
Model 5: adjusted for sex, age, CAD diagnosis, atrial fibrillation, diabetes, hypertension, all plasma lipid parameters (i.e., total, LDL, and HDL-cholesterol, triglycerides, Apo AI, Apo B, and Apo E), and CHA2DS2-VASc score.