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. 2022 Feb 4;8:781383. doi: 10.3389/fcvm.2021.781383

Table 3.

Association between high plasma concentration of Apo CIII (≥10.3 mg/dL), and ischemic stroke/TIA events by different Cox Regression models (subjects with low plasma concentration of Apo CIII, <10.3 mg/dL, are considered as reference group).

Coefficient B SE Hazard ratio
Unadjusted 1.12 0.47 3.08 (1.22–7.77)
Model 1 1.09 0.49 2.97 (1.14–7.74)
Model 2 1.05 0.49 2.86 (1.10–7.53)
Model 3 0.99 0.49 2.70 (1.03–7.13)
Model 4 1.32 0.57 3.76 (1.24–11.42)
Model 5 1.32 0.58 3.73 (1.20–11.61)

Model 1: sex- and age-adjusted.

Model 2: adjusted for sex, age, CAD diagnosis, and atrial fibrillation.

Model 3: adjusted for sex, age, CAD diagnosis, atrial fibrillation, diabetes, and hypertension.

Model 4: adjusted for sex, age, CAD diagnosis, atrial fibrillation, diabetes, hypertension, and all plasma lipid parameters (i.e., total, LDL, and HDL-cholesterol, triglycerides, Apo AI, Apo B, and Apo E).

Model 5: adjusted for sex, age, CAD diagnosis, atrial fibrillation, diabetes, hypertension, all plasma lipid parameters (i.e., total, LDL, and HDL-cholesterol, triglycerides, Apo AI, Apo B, and Apo E), and CHA2DS2-VASc score.