Table 3.

Multivariate logistic regression analysis of clinical outcomes after single or dual antiplatelet treatment.

Outcome	Unadjusted effect (95% CI)	P	Adjusted effect (95% CI)	p
Mean age (SD)-yr.	0.99 (0.97–1.02)	0.578	1.00 (0.97–1.02)	0.685
Male sex-no. (%)	1.20 (0.68–2.14)	0.530	1.30 (0.70–2.42)	0.403
Cause of stroke - no. (%)
Large-artery atherosclerosis	1
Small-vessel occlusion	0.28 (0.15–0.50)	<0.001	0.23 (0.12–0.43)	<0.001
undetermined	0.38 (0.10–1.45)	0.158	0.28 (0.07–1.13)	0.075
mRS at 90 days*	0.79 (0.62–0.99)	0.042	0.71 (0.55–0.92)	0.009
90-day mRS score 0–1*	2.17 (1.07–4.41)	0.032	2.76 (1.27–6.01)	0.010
90-day mRS score 0–2*	2.17 (0.88–5.32)	0.091
90-day mRS score 0–3	1.54 (0.47–4.99)	0.473
Recurrence of stroke within 90 days	0.93 (0.23–3.79)	0.916
Early neurological deterioration no. (%)
3d after IVT	0.68 (0.23–2.03)	0.491
7d after IVT	0.56 (0.18–1.77)	0.327
Symptomatic intracerebral hemorrhage-no. (%)	0.46 (0.04–5.14)	0.529

IVT, intravenous thrombolysis; NIHSS, National Institute of Health Stroke Scale, mRS, modified Rankin Scale based on the TOAST classification.

*Adjusted with age, sex, and cause of stroke.