Table 3.
Comparison of clinical characteristics between patients with moderate to severe (score of 2–4) and mild (score of 0–1) EPVS in the centrum semiovale (CSO) and the basal ganglia (BG).
| Mild CSO-EPVS group (score of 0–1) | Moderate to severe CSO-EPVS (score of 2–4) | P-value | Mild BG-EPVS group (score of 0-1) | Moderate to severe BG-EPVS (score of 2–4) | P-value | |
|---|---|---|---|---|---|---|
| No. | 332 | 199 | 353 | 178 | ||
| Sex, male, n (%) | 182 (54.8) | 132 (66.3) | 0.009 | 187 (53) | 127 (71.3) | <0.001 |
| BMI, kg/m2 | 23.62 [22.08–24.61] | 23.61 [21.79–24.89] | 0.976 | 23.61 [21.91–24.62] | 23.81 [22.66–24.90] | 0.026 |
| Age, years | 63 [52–71] | 64 [58–71] | 0.014 | 60 [51–67] | 69 [64–76] | <0.001 |
| Smoking, n (%) | 97 (29.2) | 83 (41.7) | 0.003 | 97 (27.5) | 83 (46.6) | <0.001 |
| Drinking, n (%) | 43 (13.0) | 36 (18.1) | 0.107 | 46 (13.0) | 33 (18.5) | 0.092 |
| Hypertension, n (%) | 152 (45.8) | 125 (62.8) | <0.001 | 148 (41.9) | 129 (72.5) | <0.001 |
| SBP, mmHg | 136.5 [122–156] | 148 [131–162] | <0.001 | 136 [120.5–155] | 150 [135.75–170] | <0.001 |
| DBP, mmHg | 85 [76–95] | 89 [79–100] | 0.003 | 85 [75.5–95] | 88.5 [80–98] | 0.004 |
| Fasting glucose, mmol/L | 5.05 [4.66–5.55] | 5.1 [4.71–5.78] | 0.115 | 5.09 [4.71–5.56] | 5.02 [4.62–5.73] | 0.690 |
| HbA1c (%) | 5.7 [5.5–5.9] | 5.8 [5.6–6.03] | 0.001 | 5.7 [5.5–5.9] | 5.9 [5.6–6.1] | <0.001 |
| Triglyceride, mmol/L | 1.13 [0.85–1.55] | 1.23 [0.93–1.81] | 0.010 | 1.17 [0.87–1.64] | 1.16 [0.91–1.66] | 0.567 |
| TC, mmol/L | 4.89 [4.23–5.73] | 4.89 [4.04–5.67] | 0.382 | 4.92 [4.22–5.84] | 4.84 [4.04–5.50] | 0.069 |
| LDL-C, mmol/L | 3.15 [2.59–3.75] | 3.04 [2.40–3.73] | 0.216 | 3.19 [2.57–3.78] | 3.06 [2.42–3.70] | 0.095 |
| HDL-C, mmol/L | 1.19 [1.04–1.42] | 1.13 [0.95–1.34] | 0.007 | 1.20 [1.05–1.42] | 1.10 [0.95–1.34] | 0.003 |
| Serum homocysteine, μmol/L | 9.35 [7.10–13.2] | 10.60 [8.10–13.6] | 0.029 | 9.2 [6.8–12.4] | 12 [8.68–16.15] | <0.001 |
| Creatinine, μmol/L | 66.40 [55.85–80.70] | 91.01 [78.50–102.31] | <0.001 | 67 [55.9–79.15] | 72.85 [62.52–84] | <0.001 |
| eGFR (mL/min per 1.73 m2) | 97.05 [83.39–106.17] | 72 [62–83.2] | 0.007 | 98.31 [84.14–107.01] | 88.66 [75.19–101.41] | <0.001 |
| Serum uric acid (μmol/L) | 329.5 [272.25–397.25] | 372 [306–444] | <0.001 | 332 [274–395] | 376 [304.75–449.5] | <0.001 |
| WBC (×109/L) | 6.86 [5.66–8.40] | 7.14 [5.74–8.96] | 0.222 | 6.86 [5.51–8.33] | 7.14 [5.81–9.06] | 0.071 |
| hs-CRP (mg/L) | 1.89 [0.50–3.36] | 2.30 [0.54–5.0] | 0.022 | 1.76 [0.50–3.30] | 2.44 [0.54–5.00] | <0.001 |
| TyG index | 8.42 [8.11–8.76] | 8.51 [8.22–8.94] | 0.004 | 8.45 [8.14–8.81] | 8.45 [8.15–8.88] | 0.578 |
BMI, body mass index; SBP, systolic blood pressure; DBP, diastolic blood pressure; HbA1c, hemoglobin A1c; TC, total cholesterol; LDL-C, low-density lipoprotein cholesterol; HDL-C, high-density lipoprotein cholesterol; eGFR, estimated glomerular filtration rate; WBC, white blood cell; hs-CRP, high-sensitivity C-reactive protein; TyG, triglyceride glucose.