Fig. 3. Linear and nonlinear dose–response relationships for early-life BMI and ovarian cancer risk.

This figure shows the results from a linear dose–response relationship with ovarian cancer; b nonlinear dose–response relationship with ovarian cancer (p-nonlinearity = 0.05). The black squares and horizontal lines represent study-specific relative risks and their 95% confidence intervals. The area of each black square reflects the weight each study contributes to the meta-analysis. The middle and horizontal tips of diamonds represent summary RRs and their 95% confidence intervals, respectively. The P values were calculated from Cochran’s Q test; all statistical tests were two-sided.