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. 2022 Feb 17;12:2717. doi: 10.1038/s41598-022-06755-x

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Susceptibility to intracranial aneurysm (Homo sapiens) based on multiple protein interactions between proteins coded by four candidate hub genes including GBA, TCF24, OLFML2A, and ARHGAP32. The network included neighboring genes correlated with four hub genes. The width of individual lines indicates the intensity of the interaction between proteins. The colors in each line indicate multiple functions including physical interaction, co-expression, prediction, co-localization, genetic interaction, pathways, and shared protein domains. The multiple protein interaction map was drawn by using the GeneMANIA program (https://genemania.org/).