Table 1:
Comparison between primary open angle glaucoma patients and controls
| Demographic and Ophthalmic Information | POAG (n = 172) | Controls (n = 179) | p-value |
|---|---|---|---|
| Age (years) | 72.9±9.0 | 70.3±8.3 | 0.005 |
| Gender (% male) | 45.3 | 40.8 | 0.39 |
| Race (% White) | 52.3 | 82.1 | <0.001 |
| BMI (kg/m2) | 27.2±4.9 | 26.8±5.4 | 0.41 |
| Type 2 diabetes (%) | 31.6 | 14.0 | <0.001 |
| Autoimmune disease (%) | 17.4 | 10.1 | 0.044 |
| Diagnosis of > 1 autoimmune disease (%) | 6.4 | 3.4 | 0.18 |
| Known diagnosis of non-infectious uveitis (%) | 2.9 | 0.6 | 0.11 |
| Any history of steroid usea (%) | 14.5 | 17.9 | 0.40 |
| BCVA (LogMAR) | 0.3±0.5 | 0.4±0.4 | 0.07 |
| HVF MD (decibels)b | −11.1±8.2 | - | - |
| IOP (mm Hg) | 16.5±5.4 | 14.8±2.6 | <0.001 |
| IOP max (mm Hg) | 25.8±7.3 | 16.0±2.7 | <0.001 |
| Cup to disc ratio | 0.8±0.1 | 0.3±0.1 | <0.001 |
All values are expressed as mean ± standard deviation unless otherwise specified. Significant p-values are in bold.
a
Any history of systemic steroid use for > 4 weeks in duration, inhaled steroid use for > 3 months in duration and topical steroid use for > 4 weeks in duration.
b
Available for 66.3% of POAG patients.
Abbreviations: BCVA, best corrected visual acuity; BMI, body mass index; HVF MD, Humphrey visual field mean deviation; IOP, intraocular pressure; LogMAR, logarithm of the minimum angle of resolution; POAG, primary open angle glaucoma.